Clinical trials for cancer drugs have three stages, Phase I–III, before marketing, each with different evaluation items. However, there is no consensus on the appropriateness of evaluation criteria for early-stage clinical ...
Apr 8, 2024
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In a small, investigator-initiated Phase II study by Dana-Farber Cancer Institute investigators, a novel combination of an antibody-drug conjugate and an immune checkpoint inhibitor showed notable activity in pre-treated ...
Apr 5, 2024
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Researchers at Fred Hutchinson Cancer Center have found that a specific subtype of a microbe commonly found in the mouth is able to travel to the gut and grow within colorectal cancer tumors. This microbe is also a culprit ...
Mar 20, 2024
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A collaborative project to bring the promise of cell therapy to patients with a deadly form of brain cancer has shown dramatic results among the first patients to receive the novel treatment. In a paper published in the New ...
Mar 13, 2024
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CureLab Oncology, a clinical-stage, pre-IPO biotech company, announced that its novel biological agent, Elenagen, has been shown to significantly enhance standard chemotherapy and provides clinical benefits for the patients ...
Feb 22, 2024
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A new research paper was published in Oncotarget, titled, "Neurotrophic-tyrosine receptor kinase gene fusion in papillary thyroid cancer: A clinicogenomic biobank and record linkage study from Finland."
Feb 20, 2024
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Imaging the tumors of patients with advanced melanoma receiving pembrolizumab (Keytruda) after only one week—rather than the standard of around three months—identified metabolic changes that corresponded with treatment ...
Jan 24, 2024
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Non-cancerous cells called stromal cells, which are found in and around prostate tumors, may be useful in assessing these tumors' potential to spread, and may even be targets for future prostate cancer treatments, according ...
Jan 18, 2024
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Cancer, as a life-threatening disease, has been a major research focus. Understanding the mechanisms of tumor progression has been a significant challenge. In recent years, increasing evidence has indicated a correlation ...
Jan 9, 2024
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The majority of patients with metastatic colorectal cancer whose cancer did not progress during initial treatment with immune checkpoint inhibitors (ICIs) had no disease progression two years after discontinuing treatment, ...
Dec 18, 2023
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