TRPM7 protein key to breast cancer metastasis in animal models
The protein transient receptor potential melastatin-like 7 (TRPM7) is a critical determinant of breast cancer cell metastasis, according to study results published in Cancer Research, a journal of the American Association for Ca ...
Cancer
Aug 07, 2012 |
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Researchers test new drug for patients with neuroendocrine tumors
A researcher at Moffitt Cancer Center and his international team of colleagues have reported study results on a novel multireceptor-targeted somatostatin analogue called pasireotide (SOM230) manufactured by Novartis Pharma ...
Cancer
Aug 06, 2012 |
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Study investigates proton radiation effects on cells
(Phys.org) -- A team of researchers at NASA's Johnson Space Center in Houston and Lawrence Berkeley National Laboratory in Berkeley, Calif., has found radiation from protons could further enhance a process that occurs during ...
Cancer
Aug 05, 2012 |
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Plant-based compound slows breast cancer in a mouse model
The natural plant compound phenethyl isothiocyanate (PEITC) hinders the development of mammary tumors in a mouse model with similarities to human breast cancer progression, according to a study published August 2 in the Journal of ...
Cancer
Aug 02, 2012 |
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Penn expert addresses ethical implications of testing for Alzheimer's disease risk
Diagnostic tests are increasingly capable of identifying plaques and tangles present in Alzheimer's disease, yet the disease remains untreatable. Questions remain about how these tests can be used in research studies examining ...
Alzheimer's disease & dementia
Jul 17, 2012 |
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Nerve growth factors elevated in pancreatic cancer model
Severe pain is a major symptom of pancreatic cancer. The results of a new study show that four different factors involved in the growth and maintenance of nerves are elevated in a mouse model of pancreatic cancer. This is ...
Cancer
Jun 19, 2012 |
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Changes in tumor size by RECIST correlate with survival
(HealthDay) -- RECIST categories used to quantify tumor changes during exposure to anticancer therapies correlate well with overall survival (OS) but reflect a more linear continuum without clear inflection ...
Cancer
Jun 13, 2012 |
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Probing the mechanism of ADAM28-mediated cancer metastasis
ADAM28, a metalloproteinase belonging to the ADAM gene family, cleaves the von Willebrand factor (VWF) and inhibits VWF-mediated cancer cell apoptosis, thereby enhancing lung metastases, so inhibiting its expression gives ...
Cancer
Jun 08, 2012 |
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Research shows promising treatments against skin cancer
Two new experimental treatments against advanced melanoma have shown promise in keeping the deadly skin cancer at bay, according to research presented in the United States on Monday.
Cancer
Jun 04, 2012 |
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Clinical trial design supports original accelerated approval of sunitinib for GIST
Patients benefitted from an important design element in the pivotal phase III clinical trial that led to Food and Drug Administration and worldwide regulatory approval of sunitinib for the treatment of gastrointestinal stromal ...
Cancer
Jun 01, 2012 |
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Pancreatectomy OK without downstaging from therapy
(HealthDay) -- Pancreatectomy improves median survival in pancreatic cancer patients even when presurgical neoadjuvant therapy does not lead to radiographic downstaging of tumors, according to a study published ...
Cancer
May 25, 2012 |
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Researchers use mathematics to fight cancer
Using mathematical models, researchers in the Integrated Mathematical Oncology (IMO) program at Moffitt Cancer Center are focusing their research on the interaction between the tumor and its microenvironment and the "selective ...
Cancer
May 03, 2012 |
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Therapy exploits 'addiction' of leukemia cells
A new study describes a therapeutic approach to halting cancer progression by exploiting a previously unrecognized "addiction" of leukemia cells to specific signaling molecules. The research, published by Cell Press online ...
Cancer
Apr 16, 2012 |
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Targeted therapeutics for colon cancer to be presented at AACR meeting
Anurag Singh, PhD, assistant professor in the Department of Pharmacology and Experimental Therapeutics at Boston University School of Medicine has been invited to present his recent work on targeted therapeutics for colon ...
Cancer
Apr 04, 2012 |
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Noninvasive imaging can detect mutations within a brain tumor
Researchers at Winship Cancer Institute have developed a technique for detecting an "oncometabolite", a chemical produced by some brain tumors' warped metabolism, via non-invasive imaging.
Cancer
Mar 22, 2012 |
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