Team finds mechanism linking key inflammatory marker to cancer
In a new study described in the journal Oncogene, researchers reveal how a key player in cell growth, immunity and the inflammatory response can be transformed into a primary contributor to tumor growth.
Cancer
May 20, 2013 |
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Simponi approved for ulcerative colitis
(HealthDay)—Simponi (golimumab) injection has been approved by the U.S. Food and Drug Administration to treat adults with moderate-to-severe ulcerative colitis.
Medications
May 15, 2013 |
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Wip1 could be new target for cancer treatment
Researchers have uncovered mutations in the phosphatase Wip1 that enable cancer cells to foil the tumor suppressor p53, according to a study in The Journal of Cell Biology. The results could provide a new ...
Cancer
May 06, 2013 |
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Two-pronged approach to immune activation could lead to vaccines that effectively shut down tumor expansion
Tumor cells often express proteins that set them apart from their healthy neighbors. These very same proteins can also help the immune system to recognize and destroy the cancer. Several research groups and ...
Cancer
Apr 26, 2013 |
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Virus-like particles provide vital clues about brain tumors
Exosomes are small, virus-like particles that can transport genetic material and signal substances between cells. Researchers at Lund University, Sweden, have made new findings about exosomes released from aggressive brain ...
Medical research
Apr 17, 2013 |
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Immune response linked to key enzyme
(Medical Xpress)—A previously unknown function of a family of enzymes familiar to biologists may contribute to scientists' understanding of signaling molecules involved in the body's immune response and ...
Immunology
Apr 12, 2013 |
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Cell-destroyer that fights and promotes TB reveals what's behind its split identity
Tumor necrosis factor—normally an infection-fighting substance produced by the body—can actually heighten susceptibility to tuberculosis if its levels are too high. University of Washington TB researchers ...
Diseases, Conditions, Syndromes
Apr 11, 2013 |
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Mitochondrial metabolic regulator SIRT4 guards against DNA damage
(Medical Xpress)—Healthy cells don't just happen. As they grow and divide, they need checks and balances to ensure they function properly while adapting to changing conditions around them.
Cancer
Apr 05, 2013 |
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Study reveals that chemotherapy works in an unexpected way
It's generally thought that anticancer chemotherapies work like antibiotics do, by directly killing off what's harmful. But new research published online on April 4 in the Cell Press journal Immunity shows that effective chemot ...
Immunology
Apr 04, 2013 |
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Team discovers how drug prevents aging and cancer progression
University of Montreal researchers have discovered a novel molecular mechanism that can potentially slows the aging process and may prevent the progression of some cancers. In the March 23 online edition of the prestigious ...
Medical research
Mar 27, 2013 |
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Functional characteristics of antitumor T cells change w increasing time after therapeutic transfer
Scientists have characterized how the functionality of genetically engineered T cells administered therapeutically to patients with melanoma changed over time. The data, which are published in Cancer Discovery, a journal of the ...
Cancer
Mar 21, 2013 |
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New cancer 'vaccine' shows future promise in treating and preventing metastatic cancers
Preclinical, laboratory studies suggest a novel immunotherapy could potentially work like a vaccine against metastatic cancers, according to scientists at Virginia Commonwealth University Massey Cancer Center. Results from ...
Cancer
Feb 27, 2013 |
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Scientists find underlying mechanisms behind chronic inflammation-associated diseases
(Medical Xpress)—Inflammatory response plays a major role in both health protection and disease generation. While the symptoms of disease-related inflammatory response have been know, scientists have not ...
Inflammatory disorders
Feb 23, 2013 |
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Researchers say silencing of retinoblastoma gene regulates differentiation of myeloid cells
Researchers at the Moffitt Cancer Center have found a potential mechanism by which immune suppressive myeloid-derived suppressor cells can prevent immune response from developing in cancer. This mechanism includes silencing ...
Immunology
Feb 19, 2013 |
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DAI provides potential imaging biomarker to indicate brain tumor response to RT
Diffusion abnormality index (DAI) shows promise as an imaging biomarker to measure brain tumor response to radiation therapy, according to research being presented at the 2013 Cancer Imaging and Radiation Therapy Symposium. ...
Cancer
Feb 08, 2013 |
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