The development of effective anti-androgen therapies for prostate cancer is a major scientific advance. However, some men who receive these targeted treatments are more likely to develop a deadly treatment-resistant prostate ...
Feb 28, 2019
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36
While many cells in our bodies can accumulate oncogenic mutations, the majority of these events do not lead to tumor formation as these abnormal cells are eliminated by defense mechanisms. Instead, tumors arise when a mutation ...
Nov 28, 2018
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137
Chess and cancer research have one thing in common: It takes strategy to defeat the opponent. And that's exactly what scientists at the MDC are doing. They are seeking to selectively make only those cancer cells aggressive ...
Nov 28, 2018
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51
Researchers have discovered that inhibiting CDK9, a DNA transcription regulator, reactivates genes that have been epigenetically silenced by cancer. Reactivation leads to restored tumor suppressor gene expression and enhanced ...
Oct 25, 2018
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1
A new innovation in cancer research will enable scientists to understand the complex causes of the disease with unprecedented speed and sophistication. This will accelerate the development of new and better treatments, and ...
Oct 18, 2018
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A little p63 goes a long way in embryonic development—and flaws in p63 can result in birth defects like cleft palette, fused fingers or even missing limbs. But once this early work is done, p63 goes silent, sitting quietly ...
Sep 18, 2018
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36
Investigators at Children's Hospital Los Angeles have been able to pinpoint the exact stage of development of the human retina, when cells can grow out of control and form cancer-like masses. The finding could open the door ...
Sep 14, 2018
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178
A treatment for highly aggressive and commonly fatal pancreatic cancer is being developed, reports a University of Houston researcher who has designed a new medicine that can inhibit two of the major pathways of the deadly ...
Sep 11, 2018
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Researchers at The University of Texas MD Anderson Cancer Center have shown how BRCA-associated protein 1 (BAP1) serves as a tumor suppressor gene in kidney, eye, bile duct, mesothelioma and other cancers by regulating a ...
Sep 10, 2018
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17
As a veterinarian, Dr. Carolyn Duregger is familiar with the telltale signs of canine melanoma. So when she gave her own dog, Parker, a routine oral examination, the 1-centimeter-diameter discolored lump in the pup's upper ...
Sep 7, 2018
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