PTEN, a tumor suppressor gene mutated in approximately 20% of primary prostate cancers, and in as many as 50% of androgen deprivation-resistant prostate cancers, relies on another gene, ARID4B, to function. These findings ...
Sep 24, 2019
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77
Researchers at The University of Texas MD Anderson Cancer Center have confirmed a protein as an oncogene responsible for the most common and lethal form of pancreatic cancer known as pancreatic ductal adenocarcinoma (PDAC). ...
Sep 4, 2019
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1114
One of the most extensively studied genes in cancer, TP53 is well known for its role as a tumor suppressor. It senses cellular stress or damage, and in response stops cell division or initiates cell death, thereby preventing ...
Jul 30, 2019
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285
Now, a new Salk Institute study, published on July 24, 2019, in the journal Science Advances, shows that researchers could target these hard-to-treat cancers by pursuing drugs that keep a cellular "switch," called CREB, from ...
Jul 24, 2019
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51
In a study published online in Nature on June 26, research teams led by Dr. Yang Weiwei at the Institute of Biochemistry and Cell Biology of the Chinese Academy of Sciences (CAS) and Dr. Li Guohui from the Dalian Institute ...
Jun 26, 2019
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0
Your mother was right: Broccoli is good for you. Long associated with decreased risk of cancer, broccoli and other cruciferous vegetables—the family of plants that also includes cauliflower, cabbage, collard greens, Brussels ...
May 16, 2019
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6993
Analyzing both the entire set of genes and all the proteins produced by colon cancer tissues from patient samples has revealed a more comprehensive view of the tumor that points at novel cancer biological mechanisms and possible ...
Apr 25, 2019
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173
A few months ago, Lisa Diller saw a family for a consultation in her cancer clinic. Their story is one of tragedy, and of hope.
Apr 1, 2019
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0
Choroid plexus carcinoma (CPC) is a particularly challenging type of brain cancer. The tumor most commonly arises in infants under the age of one—who are too young to undergo radiation treatment. Only 40 percent of children ...
Mar 27, 2019
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1
Scientists have long known that the protein p53, when mutated, is a critical factor in the onset of many different kinds of cancer. In its unmutated form, however, it is known to protect against cancer.
Mar 18, 2019
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