Scientists have long known that the protein p53, when mutated, is a critical factor in the onset of many different kinds of cancer. In its unmutated form, however, it is known to protect against cancer.
Mar 18, 2019
0
449
During carcinogenesis, malignant cells undergo uncontrolled division, causing tumor dissemination. Target therapy is an actively developing area of cancer treatment that includes blocking the action of certain proteins that ...
Aug 2, 2018
0
3
Researchers at the Federal University of Rio de Janeiro (UFRJ) and the State University of Rio de Janeiro (UERJ) have made a discovery that could lead to the development of a treatment against more than half of breast cancer ...
Jun 27, 2018
0
13
A protein in the cell nucleus already targeted therapeutically for several types of cancer has now been linked to an aggressive form of pediatric liver cancer called hepatoblastoma (HBL), according to a study published in ...
Jun 11, 2018
0
1
New research published in Molecular Oncology may help explain why African American men are at a higher risk of being diagnosed with prostate cancer and a higher risk of dying from the disease compared with European American ...
May 9, 2018
0
4
Research led by UNC School of Medicine student Wesley Stepp, Ph.D., shows how more detailed genetic testing of head and neck tumors could lead to more personalized treatments for patients.
Apr 26, 2018
0
1
An international team of researchers has discovered a new anti-cancer protein. The protein, called LHPP, prevents the uncontrolled proliferation of cancer cells in the liver. The researchers led by Prof. Michael N. Hall from ...
Mar 21, 2018
0
1420
So-called "triple-negative" breast cancer is a particularly aggressive and difficult-to-treat form. It accounts for only about 10 percent of breast cancer cases, but is responsible for about 25 percent of breast cancer fatalities.
Nov 20, 2017
0
352
There are two important categories of genes involved in cancer development, oncogenes and tumor suppressor genes. When oncogenes gain function, e.g. through mutation, they actively promote cancer - drugs that turn them off ...
Oct 10, 2017
0
1
Cells are constantly turning proteins on and off via molecular switches—phosphate molecules—that have become common drug targets. in a new study, lung cancer tumors were prevented in mice by a novel small molecule that ...
May 16, 2017
0
2
