An international clinical trial of a treatment for advanced urothelial cancer has found a new dual therapy can nearly double patients' life expectancy.
Jan 9, 2024
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A combination immunotherapy treatment of nivolumab plus ipilimumab was associated with no improvement in survival for advanced cancers other than melanoma, when compared to nivolumab alone, according to a recent Northwestern ...
Sep 22, 2023
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Why are some bladder cancers resistant to a type of immunotherapy called immune checkpoint inhibitors? Penn State College of Medicine researchers have found that the genetic and pathologic diversity of cells within the tumor ...
Mar 31, 2023
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A new research paper titled "Attenuation of cancer proliferation by suppression of glypican-1 and its pleiotropic effects in neoplastic behavior" has been published in Oncotarget.
Mar 22, 2023
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Nectin-4 has been successfully established as a target molecule in locally advanced and metastatic bladder cancer. An antibody-drug conjugate (enfortumab-vedotin) directed against nectin-4 has shown marked tumor remission ...
Nov 3, 2022
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Urothelial carcinoma (UC) is one of the most common malignancies genitourinary cancers, including upper tract urothelial carcinoma (UTUC) and urothelial carcinoma of the bladder (UCB).
Jul 26, 2022
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Hundreds of chemical compounds were screened on cell cultures representing different stages and subtypes of bladder cancer and several promising agents with inhibitory (growth-inhibiting) effects were identified. A drug used ...
Apr 11, 2022
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Analysis of DNA copy number variants (CNVs) in the cells exfoliated in urine showed better sensitivity and similar specificity in detecting urothelial carcinoma compared with urine cytology, according to results published ...
Oct 9, 2020
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The over-prescribing of antibiotics is reducing survival rates in patients with urothelial carcinoma and it needs to be stopped to avoid the serious risk posed by resistant bacterial infections, according to a new medical ...
Aug 17, 2020
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(HealthDay)—For patients with locally advanced upper tract urothelial carcinoma (UTUC), gemcitabine-platinum combination chemotherapy improves disease-free survival, according to a study published online March 5 in The ...
Mar 17, 2020
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