The body's defense strategies against viral infections are as diverse as the attacks themselves. A team from the Technical University of Munich (TUM) and the Max Planck Institute for Biochemistry has conducted a systematic ...
Mar 4, 2019
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Experimental gene therapy cassettes for Duchenne muscular dystrophy have been modified to deliver better performance. The cassettes, which carry the therapy into muscle cells, contain newer versions of a miniaturized treatment ...
Feb 1, 2019
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UCLA researchers led by Dr. Donald Kohn have created a method for modifying blood stem cells to reverse the genetic mutation that causes a life-threatening autoimmune syndrome called IPEX. The gene therapy, which was tested ...
Jan 11, 2019
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Mammalian cells seem to be able to memorize anti-viral stimulation at the level of DNA-packaging molecules, enabling faster and greater activation of anti-viral genes in subsequent stimulations, according to a study conducted ...
Oct 25, 2018
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Viral vectors used to deliver gene therapies undergo spontaneous changes during manufacturing which affects their structure and function, found researchers from the Perelman School of Medicine at the University of Pennsylvania ...
Oct 18, 2018
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A gene signature in the bloodstream could reveal whether someone is going to develop active tuberculosis (TB) disease months before symptoms begin. Such a signature has now been developed by a team led by the Francis Crick ...
Jun 19, 2018
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A UMD researcher has uncovered new mechanisms that dictate the development of germline stem cells or germ cells, the only cell type capable of passing genetic information on to the next generation. Stem cell research is on ...
Apr 30, 2018
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Zebrafish, roundworms, fruit flies, mice, rats, rabbits, dogs, cats, pigs, and monkeys provide steppingstones to clinical trials to evaluate new treatments for people. The value of animal studies continues, even after a new ...
Mar 30, 2018
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Once herpes simplex infects a person, the virus goes into hiding inside nerve cells, hibernating there for life, periodically waking up from its sleep to reignite infection, causing cold sores or genital lesions to recur.
Mar 15, 2018
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For nearly 20 years, Tatyana Golovkina, PhD, a microbiologist, geneticist and immunologist at the University of Chicago, has been working on a particularly thorny problem: Why are some people and animals able to fend off ...
Aug 15, 2017
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