News tagged with viral rna
What role do processing bodies play in cell survival and protection against viral infection?
As scientists learn more about processing bodies (PBs), granules present within normal cells, they are unraveling the complex role PBs play in maintaining cellular homeostasis by regulating RNA metabolism ...
Medical research
May 16, 2013 |
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Protein implicated in lupus promotes disease progression by distinct mechanisms in different immune cells
Patients with systemic lupus erythematosus (SLE) come under attack by their immune system, producing 'autoantibodies' that inflict damage throughout the body. Antibodies normally target foreign proteins, ...
Immunology
Mar 13, 2013 |
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West Nile virus passes from female to eggs, but less so from larvae to adults
In California Culex mosquitoes are considered to be the principle vectors of West Nile virus (WNV), which infects birds, humans, and other mammals during the summer. In addition, these mosquitoes may also serve as overwintering ...
Diseases, Conditions, Syndromes
Mar 05, 2013 |
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Computer modeling reveals how surprisingly potent hepatitis C drug works
A study by researchers from Los Alamos National Laboratory and a multinational team reveals how daclatasvir, a direct-acting antiviral agent in development for the treatment of hepatitis C virus (HCV), targets one of its ...
Diseases, Conditions, Syndromes
Feb 18, 2013 |
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Immune system foiled by a hairpin
The innate immune system detects invasive pathogens and activates defense mechanisms to eliminate them. Pathogens, however, employ a variety of tricks to block this process. A new study shows how the measles virus thwarts ...
Immunology
Jan 22, 2013 |
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Foot soldiers of the immune system: IFIT antiviral protein recognizes foreign RNA and blocks viral infections
Researchers at McGill University and the Research Center for Molecular Medicine (CeMM) of the Austrian Academy of Sciences have discovered the molecular blueprint behind the IFIT protein. This key protein enables the human ...
Immunology
Jan 13, 2013 |
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Researchers describe elusive replication machinery of flu viruses
Scientists at The Scripps Research Institute (TSRI) have made a major advance in understanding how flu viruses replicate within infected cells. The researchers used cutting-edge molecular biology and electron-microscopy ...
Medical research
Nov 22, 2012 |
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Discovery advances fight against phleboviruses
(Medical Xpress)—Researchers in the Life Sciences Institute at the University of Michigan have discovered how a particular type of virus hides and protects its genetic information from the immune system, ...
Medical research
Nov 07, 2012 |
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Field guide to the Epstein-Barr virus charts viral paths toward cancer
Researchers from The Wistar Institute and Memorial Sloan-Kettering Cancer Center (MSKCC) have teamed to publish the first annotated atlas of the Epstein-Barr virus genome, creating the most comprehensive ...
Medical research
Aug 23, 2012 |
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Catching the cap-snatcher: Structural analysis opens the way to new anti-influenza drugs
Researchers at the European Molecular Biology Laboratory (EMBL) in Grenoble, France, have determined the detailed 3-dimensional structure of part of the flu virus' RNA polymerase, an enzyme that is crucial for influenza virus ...
Diseases, Conditions, Syndromes
Aug 02, 2012 |
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Infection warning system in cells contains targets for antiviral and vaccine strategies
Two new targets have been discovered for antiviral therapies and vaccines strategies that could enhance the body's defenses against such infectious diseases as West Nile and hepatitis C. The targets are within the infection ...
Immunology
Jul 30, 2012 |
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'Junk DNA' can sense viral infection
Once considered unimportant "junk DNA," scientists have learned that non-coding RNA (ncRNA) RNA molecules that do not translate into proteins play a crucial role in cellular function. Mutations in ncRNA are ...
Medical research
Apr 24, 2012 |
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First-ever integrative 'Omics' profile lets scientist discover, track his diabetes onset
Geneticist Michael Snyder, PhD, has almost no privacy. For more than two years, he and his lab members at the Stanford University School of Medicine pored over his body's most intimate secrets: the sequence of his DNA, the ...
Genetics
Mar 15, 2012 |
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Hepatitis C virus survives by hijacking liver microRNA: study
Viral diseases are still one of the biggest challenges to medical science. Thanks to thousands of years of co-evolution with humans, their ability to harness the biology of their human hosts to survive and thrive makes them ...
Diseases, Conditions, Syndromes
Jan 02, 2012 |
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Scientists find potential Achilles' heel on Lassa fever and related viruses
Scientists at The Scripps Research Institute have determined the atomic structure of a protein that the Lassa fever virus uses to make copies of itself within infected cells. The structural data reveal an ...
Medical research
Nov 15, 2011 |
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