Viral Vectors delivery new calcium pumps for ailing hearts
(Medical Xpress)—A fresh round of trials to evaluate gene therapy for the heart is set to begin in a couple of weeks. The British Heart Foundation will be sponsoring the study, which seeks to replace defective ...
Medical research
May 01, 2013 |
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Recipe for large numbers of stem cells requires only one ingredient
Stem cells and tissue-specific cells can be grown in abundance from mature mammalian cells simply by blocking a certain membrane protein, according to scientists at the University of Pittsburgh School of Medicine and the ...
Medical research
Apr 17, 2013 |
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Researchers show that lipid nanoparticles are ideal for delivering genes and drugs
Researchers from Basque Public University are using nanotechnology to develop new formulations that can be applied to drugs and gene therapy. Specifically, they are using nanoparticles to design systems for ...
Genetics
Feb 28, 2013 |
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Gene therapy cocktail shows promise in long-term clinical trial for rare fatal brain disorder
Results of a clinical trial that began in 2001 show that a gene therapy cocktail conveyed into the brain by a molecular special delivery vehicle may help extend the lives of children with Canavan disease, a rare and fatal ...
Medical research
Dec 19, 2012 |
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Dengue vaccine to be tested in India
French health care giant Sanofi Pasteur will soon test a vaccine against dengue fever in India amid concerns about the increasingly global spread of the disease, reports said Monday.
Diseases, Conditions, Syndromes
Nov 19, 2012 |
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Stem cell scientists discover potential way to expand cells for use with patients
Canadian and Italian stem cell researchers have discovered a new "master control gene" for human blood stem cells and found that manipulating its levels could potentially create a way to expand these cells for clinical use.
Medical research
Nov 08, 2012 |
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Mouse model could help identify viral vectors that may cause tumors
Investigators at Nationwide Children's Hospital have identified a mouse model that could help evaluate the risk that viral vectors used in gene therapy might promote tumor formation as a side-effect. The study appears in ...
Cancer
Oct 26, 2012 |
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Stem cell therapy for spinal cord injury
Stem cells are considered promising agents for the recovery of spinal cord injuries. European scientists explore their abilities and plan future therapeutic strategies.
Medical research
Sep 25, 2012 |
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New framework for more effective vaccine vectors
Despite the development of new technologies for successful vaccination against contagious diseases and cancer, there is a lack of standard operation procedures (SOPs) and cross-comparison. European scientists ...
Medical research
Sep 20, 2012 |
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Retina transplantation improved by manipulating recipient retinal microenvironment
A research team in the United Kingdom has found that insulin-like growth factor (IGF1) impacts cell transplantation of photoreceptor precursors by manipulating the retinal recipient microenvironment, enabling better migration ...
Ophthalmology
Jul 11, 2012 |
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New gene transfer strategy shows promise for limb girdle and other muscular dystrophies
The challenge of treating patients with genetic disorders in which a single mutated gene is simply too large to be replaced using traditional gene therapy techniques may soon be a thing of the past. A Nationwide Children's ...
Genetics
Jul 09, 2012 |
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An economical, effective and biocompatible gene therapy strategy promotes cardiac repair
Dr Changfa Guo, Professor Chunsheng Wang and their co-investigators from Zhongshan hospital Fudan University, Shanghai, China have established a novel hyperbranched poly(amidoamine) (hPAMAM) nanoparticle based hypoxia regulated ...
Medical research
Jul 06, 2012 |
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Successful transplant of patient-derived stem cells into mice with muscular dystrophy
Stem cells from patients with a rare form of muscular dystrophy have been successfully transplanted into mice affected by the same form of dystrophy, according to a new study published today in Science Tr ...
Medical research
Jun 27, 2012 |
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Transgenic technique to 'eliminate' a specific neural circuit of the brain in primates
Japanese researchers developed a gene transfer technique that can "eliminate" a specific neural circuit in non-human primates for the first time in the world.
Neuroscience
Jun 26, 2012 |
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The neurological basis for fear and memory
Fear conditioning using sound and taste aversion, as applied to mice, have revealed interesting information on the basis of memory allocation.
Neuroscience
Jun 18, 2012 |
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