Using a newly developed mouse model of acute lung injury, researchers found that exposure to the SARS-CoV-2 spike protein alone was enough to induce COVID-19-like symptoms including severe inflammation of the lungs.
Apr 27, 2021
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An international team of scientists have identified antibodies that neutralize omicron and other SARS-CoV-2 variants. These antibodies target areas of the virus spike protein that remain essentially unchanged as the viruses ...
Dec 27, 2021
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Most research on immunity to the SARS-CoV-2 virus and COVID-19 vaccine development has focused on antibody responses to the spike protein and other viral surface proteins. But antibodies that recognize the virus's internal ...
Jun 24, 2022
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Human cytomegalovirus is a leading cause of birth defects and transplant failures. As it's evolved over time, this virus from the herpes family has found a way to bypass the body's defense mechanisms that usually guards against ...
Aug 28, 2018
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Scientists have known for a while that SARS-CoV-2's distinctive "spike" proteins help the virus infect its host by latching on to healthy cells. Now, a major new study shows that they also play a key role in the disease itself.
Apr 30, 2021
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When looking at the state of COVID-19 in the United States, Mansoor Amiji, distinguished professor in the Department of Pharmaceutical Sciences at Northeastern, invites you to think from the perspective of a virus. What does ...
Jun 10, 2022
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The latest results from the phase 3 COVID-19 vaccines trials have been very positive. These have shown that vaccinating people with the gene for SARS-CoV-2 spike protein can induce excellent protective immunity.
Dec 10, 2020
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Adenoviruses have a linchpin protein that stabilizes their DNA until it reaches the infected cell's nucleus. The protein then detaches from the viral genome, and the virus uncoats. Only then are the genes released into the ...
Dec 21, 2021
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Alzheimer's disease can begin almost imperceptibly, often masquerading in the early months or years as forgetfulness that is common in older age. What causes the disease remains largely a mystery.
Jul 29, 2022
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A new potential drug target has been identified in SARS CoV-2—the virus that causes COVID-19—by scientists at the Center of Structural Genomics of Infectious Diseases, or CSGID, who say multiple drugs will be needed to ...
Mar 20, 2020
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