Immunology

When liver immune cells turn bad

A high-fat diet and obesity turn "hero" virus-fighting liver immune cells "rogue", leading to insulin resistance, a condition that often results in type 2 diabetes, according to research published today in Science Immunology.

Medical research

Turning 'bad' fat into 'good': A future treatment for obesity?

By knocking down the expression of a protein in rat brains known to stimulate eating, Johns Hopkins researchers say they not only reduced the animals' calorie intake and weight, but also transformed their fat into a type ...

Cardiology

Unsaturated fats, high-quality carbs lower risk of heart disease

While eliminating saturated fats can improve heart health, a new study shows that it makes a difference which foods are used in their place. A study published today in the Journal of the American College of Cardiology shows ...

Medical research

Researchers identify "beige" fat-burning cells in humans

For the first time, a research team, led by a UC San Francisco biologist, has isolated energy-burning "beige" fat from adult humans, which is known to be able to convert unhealthy white fat into healthy brown fat. The scientists ...

Medical research

Heart hormone helps shape fat metabolism

It's well known that exercising reduces body weight because it draws on fat stores that muscle can burn as fuel. But a new study at Sanford-Burnham Medical Research Institute (Sanford-Burnham) suggests that the heart also ...

Medical research

Molecule produced by fat cells reduces obesity and diabetes in mice

UC San Francisco researchers have discovered a new biological pathway in fat cells that could explain why some people with obesity are at high risk for metabolic diseases such as type 2 diabetes. The new findings—demonstrated ...

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