Oncology & Cancer

Understanding why men get more cancer than women

Peter Mac-led research has shed new light on why men are more likely than women to get cancer, uncovering a new role for the X chromosome in affecting cancer risk and mortality.

Genetics

For keeping X chromosomes active, chromosome 19 marks the spot

After nearly 40 years of searching, Johns Hopkins researchers report they have identified a part of the human genome that appears to block an RNA responsible for keeping only a single X chromosome active when new female embryos ...

Neuroscience

Engineered flies spill secret of seizures

In a newly reported set of experiments that show the value of a particularly precise but difficult genetic engineering technique, researchers at Brown University and the University of California–Irvine have created a Drosophila ...

Diseases, Conditions, Syndromes

X marks the spot -- TBL1X gene involved in autism spectrum disorder

Autism Spectrum Disorder (ASD) affects about 1 in 100 children resulting in a range of problems in language, communication and understanding other people's emotional cues, all of which can lead to difficulties in social situations. ...

Genetics

Meet CLAMP: A newly found protein that regulates genes

(Medical Xpress)—A newly discovered protein, found in many species, turns out to be the missing link that allows a key regulatory complex to find and operate on the lone X chromosome of male fruit flies, bringing them to ...

Genetics

Homing in on developmental epigenetics

Germ cells have unique molecular features that enable them to perform the important task of transmitting genetic information to the next generation. During development from their embryonic primordial state, germ cells are ...

Genetics

Early menopause in mice: A model of human POI

(Medical Xpress)—Scientists have established a genetic mouse model for primary ovarian insufficiency (POI), a human condition in which women experience irregular menstrual cycles and reduced fertility, and early exposure ...

Genetics

Famous cancer-fighting gene also protects against birth defects

New research has revealed how the famous tumour suppressor gene p53 is surprisingly critical for development of the neural tube in female embryos. This is important because healthy development of the neural tube is needed ...

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