Oncology & Cancer

Gene discovery may explain female melanoma survival advantage

Centenary Institute scientists have discovered that genes on the X chromosome may be key to the improved survival rates of females with melanoma–as compared to their male counterparts. The findings could ultimately lead ...

Genetics

Researchers generate complete human X chromosome sequence

Researchers at the National Human Genome Research Institute (NHGRI), part of the National Institutes of Health (NIH), have produced the first end-to-end DNA sequence of a human chromosome. The results, published today in ...

Oncology & Cancer

Understanding why men get more cancer than women

Peter Mac-led research has shed new light on why men are more likely than women to get cancer, uncovering a new role for the X chromosome in affecting cancer risk and mortality.

Diseases, Conditions, Syndromes

For this mom, rare bone disease is a family affair

Most people expect some risk in activities like mountain biking or rollerblading, but few would expect to end up in the emergency room with a broken thigh bone from doing a squat.

Immunology

Unlocking the female bias in lupus

The autoimmune disease lupus, which can cause fatigue, a facial rash, and joint pain, strikes females far more often than males. Eight-five percent of people with lupus are female, and their second X chromosome seems partly ...

Oncology & Cancer

Muscle gene mutations implicated in human nasal/sinus cancer

By sequencing the entire genomes of tumor cells from six people with a rare cancer of the nose and sinus cavity, Johns Hopkins researchers report they unexpectedly found the same genetic change¾one in a gene involved in ...

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