Oncology & Cancer

Overstuffed cancer cells may have an Achilles' heel

In a study using yeast cells and data from cancer cell lines, Johns Hopkins University scientists report they have found a potential weak spot among cancer cells that have extra sets of chromosomes, the structures that carry ...

Alzheimer's disease & dementia

New light shed on early stage Alzheimer's disease

The disrupted metabolism of sugar, fat and calcium is part of the process that causes the death of neurons in Alzheimer's disease. Researchers from Karolinska Institutet in Sweden have now shown, for the first time, how important ...

Diseases, Conditions, Syndromes

New antifungal provides hope in fight against superbugs

Microscopic yeast have been wreaking havoc in hospitals around the world—creeping into catheters, ventilator tubes, and IV lines—and causing deadly invasive infection. One culprit species, Candida auris, is resistant ...

Genetics

Weill Institute researchers uncover basic cell pathway

Although all cells in an organism have the same DNA, cells function differently based on the genes they express. While most studies of gene expression focus on activities in the cell's nucleus, a new Cornell study finds that ...

Medical research

Complex cellular machine visualized to yield new insights in cancer

Cellular machines that control chromosome structure, such as the RSC complex, are mutated in about one-fifth of all human cancers. Now, for the first time, scientists have developed a high-resolution visual map of this multi-protein ...

Medical research

A new puzzle piece to control the aging and age-related diseases

A basic discovery of how the cellular functions are connected to control aging is presented in the journal Cell Metabolism. The study shows that an increasingly deteriorating communication between the cells' organelles is ...

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