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Scientists identify promising new target for Alzheimer's-linked brain inflammation
A multidisciplinary team has developed a selective compound that inhibits an enzyme tied to inflammation in people at genetic risk for Alzheimer's, while preserving normal brain function and crossing the blood-brain barrier.
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Medical research news
Mix of different types of physical activity may be best for longer life
Regularly doing a mix of different types of physical activity may be best for prolonging the lifespan, but the associations aren't linear, pointing to a possible optimal threshold effect, suggests research published in the ...
11 hours ago
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Internet Gaming Disorder is affecting a significant portion of young adults
Researchers out of Spain and Italy report a globally pooled Internet Gaming Disorder prevalence of 6.1% among adults ages 18–35. Internet Gaming Disorder is considered a condition for further study in DSM-5-TR, with official ...
Community water fluoridation not linked to lower birth weight, large US study finds
A new study from Columbia University Mailman School of Public Health finds that community water fluoridation (CWF) is not associated with significant changes in birth weight—a widely accepted indicator of infant health ...
11 hours ago
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Unexpected vitamin B1 connection emerges in genetic study of gut motility
Bowel habits aren't exactly dinner-table talk. But they reflect how quickly the gut moves things along, and when that goes wrong, people can experience constipation, diarrhea, or irritable bowel syndrome (IBS). Yet the biological ...
20 hours ago
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Dual gene deletion reveals potential biomarkers for predicting immunotherapy success
The deletion of two cancer genes, CHD1 and MAP3K7, improves how well tumors respond to cancer immunotherapy and could be used as biomarkers to help predict which patients are most likely to benefit from treatment, new research ...
12 hours ago
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A closer look at how local protein production is altered in ALS
The functioning of neurons, cells that transmit information in the nervous system, heavily relies on the production of proteins. Proteins are synthesized both inside cells (i.e., in the soma) and locally along axons, projections ...
An oral cancer drug shows promise against aggressive brain tumors
A national clinical trial led by the Alliance for Clinical Trials in Oncology has found that abemaciclib, an oral cancer drug, may slow tumor growth in patients with aggressive meningiomas that have specific genetic mutations. ...
14 hours ago
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B cells play a more sinister role than believed in progression of type 1 diabetes
A recent study by Vanderbilt Health researchers has revealed a greater, detrimental role for B lymphocytes (B cells) in the progression of type 1 diabetes (T1D).
14 hours ago
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Exposure to wildfire smoke late in pregnancy may raise autism risk in children
Exposure to wildfire smoke during the final months of pregnancy may raise the risk that a child is later diagnosed with autism, according to a new study led by Tulane University researchers.
13 hours ago
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Qatari genetic map reveals over 150,000 structural variants
Research co-led by King's College London and Sidra Medicine, Qatar, has produced the most detailed map to date of large-scale genetic differences in the Qatari population, providing a clearer picture of the genetic diversity ...
15 hours ago
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New AI uncovers hidden patterns in biomedical knowledge graphs
A new artificial intelligence (AI) method called BioPathNet helps researchers systematically search large biological data networks for hidden connections—from gene functions and disease mechanisms to potential therapeutic ...
15 hours ago
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Blocking immune cells in the brain can prevent infantile amnesia
Scientists have found that blocking microglia (specialist immune cells in the brain) prevents infant forgetting ("infantile amnesia") and improves memory in mice, suggesting that microglia may actively manage memory formation ...
15 hours ago
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Preventing 'spermageddon'—discovery of an immune-like mechanism that protects fertility
New insights into a sophisticated process that protects sperm cells has revealed a mechanism, similar to an immune system, thwarts genetic chaos during the earliest stages of their development.
16 hours ago
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Blood test can identify cancer in patients with non-specific symptoms
A simple blood test can help detect cancer in patients with non-specific symptoms such as fatigue, pain or weight loss. This is according to a Swedish study from Karolinska Institutet, Danderyd Hospital and others, published ...
18 hours ago
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Memory justifications remain surprisingly stable even as memories fade over time, study shows
While memories may fade with time, the explanations people give for why they remember an event remain surprisingly stable and reliable, according to a new study by Ben-Gurion University of the Negev.
17 hours ago
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Potential new target to treat Parkinson's disease discovered
About 1 million Americans suffer from Parkinson's disease, with around 90,000 new cases diagnosed each year, according to the Parkinson's Foundation. The chronic, degenerative brain disorder destroys dopamine-producing cells ...
19 hours ago
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Air pollution may increase the risk of the neurodegenerative disease ALS
Prolonged exposure to air pollution can be linked to an elevated risk for serious neurodegenerative diseases like ALS and seems to speed up the pathological process, report researchers from Karolinska Institutet in Sweden. ...
18 hours ago
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Noninvasive brain scanning could send signals to paralyzed limbs
People with spinal cord injuries often lose some or all their limb function. In most patients, the nerves in their limbs work fine, and the neurons in their brain are still operational, but the damage to their spinal cords ...
18 hours ago
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