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Immunology
How immune cells communicate to fight viruses: New mouse model enables identification of chemokine producers and sensors
Chemokines are signaling proteins that orchestrate the interaction of immune cells against pathogens and tumors. To understand this complex network, various techniques have been developed to identify chemokine-producing cells.
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Neuroscience
Creatine found to improve cognitive performance during sleep deprivation
Creatine is a popular dietary supplement in the sports community that is used to improve physical performance. Researchers at Forschungszentrum Jülich have now discovered that a high single dose of creatine can temporarily ...
1 hour ago
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Medical research news
Using AI to improve diagnosis of rare genetic disorders
Diagnosing rare Mendelian disorders is a labor-intensive task, even for experienced geneticists. Investigators at Baylor College of Medicine are trying to make the process more efficient using artificial intelligence. The ...
3 hours ago
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Identifying a new liver defender: The role of resident macrophages
Osaka University researchers have discovered liver resident macrophages' pivotal role in defending against gut bacteria and related substances entering via the portal vein, particularly under compromised intestinal barrier ...
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Differentiating cerebral cortical neurons to decipher molecular mechanisms of neurodegeneration
A research team led by Professor Haruhisa Inoue (Department of Cell Growth and Differentiation) derived iPS cells (iPSC) from α-synucleinopathy patients with early-onset familial Parkinson's disease (PD) carrying the α-synuclein ...
1 hour ago
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National trial safely scales back prescribing of a powerful antipsychotic for the elderly
Warning letters from Medicare can safely cut prescribing of a powerful but risky antipsychotic, according to a new study at Columbia University Mailman School of Public Health. Researchers used Medicare data to study the ...
1 hour ago
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With hybrid brains, these mice smell like a rat
If mice ever wonder what it's like to experience the world as a rat, some are now able to live that dream, at least when it comes to the sense of smell.
1 hour ago
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Premature mortality higher among sexual minority women, study finds
Compared to heterosexual women, bisexual women died 37% sooner and lesbian women 20% sooner, according to results from one of the largest studies to examine sexual orientation-related inequities in mortality and the first ...
1 hour ago
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Researchers create an AI-powered digital imaging system to speed up cancer biopsy results
University of Waterloo researchers have invented a digital medical imaging system that significantly improves the cancer detection process to deliver immediate results and enable swift, effective treatment for all types of ...
2 hours ago
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Understanding the cellular mechanisms of obesity-induced inflammation and metabolic dysfunction
A South Korean team has spearheaded a research endeavor that successfully uncovered the mechanisms governing inflammation and metabolic dysfunction in tissues associated with obesity. Their findings were published in Nature ...
2 hours ago
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Genetic variations may predispose people to Parkinson's disease following long-term pesticide exposure, study finds
A new UCLA Health study has found that certain genetic variants could help explain how long-term pesticide exposure could increase the risk of Parkinson's disease.
7 hours ago
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Researchers publish final results of key clinical trial for gene therapy for sickle cell disease
In a landmark study, an international consortium led by researchers at Children's Hospital of Philadelphia (CHOP) published the final results of a key clinical trial of the gene therapy CASGEVY (exagamglogene autotemcel) ...
3 hours ago
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Study reveals tai chi benefits for sleep quality in advanced lung cancer patients
A research team from the School of Nursing, LKS Faculty of Medicine of the University of Hong Kong (HKUMed), found positive effects of tai chi and aerobic exercise on sleep quality, psychological well-being, physical function, ...
3 hours ago
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Link between depression and cardiovascular disease explained: They partly develop from same gene module
Depression and cardiovascular disease (CVD) are serious concerns for public health. Approximately 280 million people worldwide have depression, while 620 million people have CVD.
11 hours ago
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Research identifies pitfalls and opportunities for generative AI in patient messaging systems
A new study by investigators from Mass General Brigham demonstrates that large language models (LLMs), a type of generative AI, may help reduce physician workload and improve patient education when used to draft replies to ...
17 hours ago
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A closed-loop drug-delivery system could improve chemotherapy
When cancer patients undergo chemotherapy, the dose of most drugs is calculated based on the patient's body surface area. This is estimated by plugging the patient's height and weight into an equation, dating to 1916, that ...
19 hours ago
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New AI technology estimates brain age using low-cost EEG device
As people age, their brains do, too. But if a brain ages prematurely, there is potential for age-related diseases such as mild cognitive impairment, dementia, or Parkinson's disease. If "brain age" could be easily calculated, ...
19 hours ago
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It's easier now to treat opioid addiction with medication—but use has changed little, study finds
For years, even as opioid overdose deaths dramatically increased, doctors and other prescribers in the United States needed special permission from the federal government if they wanted to prescribe buprenorphine, a medication ...
19 hours ago
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Alteration of brain network condition could predict painful vaso-occlusive crisis in patients with sickle cell disease
A new study led by Indiana University School of Medicine researchers has found that a brain network condition called "explosive synchronization" could be the cause of extreme pain crises in people with sickle cell disease.
21 hours ago
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New device improves stem cell generation and chance for accessible Alzheimer's cell therapy
Researchers in Sweden say they have improved on a technique for converting regular skin cells into neural stem cells—an advance that they say helps close the gap for accessible personalized cell-based therapies for Alzheimer's ...
21 hours ago
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