Microglia are primary immune cells that safeguard the mammalian brain, partly by devouring or 'phagocytosing' pathogens and toxic debris. Recent genetic studies have consistently highlighted the role of microglia in the development ...
New imaging of patients with Alzheimer's demonstrates how a telltale protein spreads throughout the brain based on the phenotype of the disease, i.e., whether the condition is dominated by forgetfulness, or atrophy in a specific ...
Researchers at Emory University School of Medicine have recently carried out a large-scale analysis of the brains of patients with Alzheimer's disease (AD). Their findings, published in Nature Neuroscience, unveiled a series ...
Two drugs approved decades ago not only counteract brain damage caused by Alzheimer's disease in animal models, the same therapeutic combination may also improve cognition.
A newly discovered gene mutation linked to early onset Alzheimer's disease has been discovered by an international team of scientists, who traced the DNA flaw through multiple members of a single family.
About one in every five people carries a version of a gene that—although largely unsung—appears to confer protection against both Alzheimer's disease and Parkinson's disease, Stanford Medicine investigators and their ...
Aug 30, 2023
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Losing the activity of a key ion channel in the brain may contribute to the buildup of a devastating and toxic protein responsible for the clumps of plaque that accumulate in Alzheimer's disease, a team of neurobiologists ...
Researchers led by the Beth Israel Deaconess Medical Center, Boston, have examined how a dementia diagnosis impacts medication use patterns in older adults.
Cognitive decline associated with Alzheimer's disease (AD) develops when neurons begin to die, which can be caused by inappropriate immune responses and excessive inflammation in the brain triggered by amyloid beta deposits ...
Aug 25, 2023
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Researchers at Washington University School of Medicine in St. Louis have identified proteomic changes associated with forms of Alzheimer's disease (AD). In a paper, "Proteomics of brain, CSF, and blood identifies molecular ...
