Arthritis & Rheumatism

3-D bioprinting constructs for cartilage regeneration

Cartilage injury is a common cause of joint dysfunction and existing joint prostheses cannot remodel with host joint tissue. However, it is challenging to develop large-scale biomimetic anisotropic constructs that structurally ...

Arthritis & Rheumatism

Potential arthritis treatment prevents cartilage breakdown

Osteoarthritis, a disease that causes severe joint pain, affects more than 20 million people in the United States. Some drug treatments can help alleviate the pain, but there are no treatments that can reverse or slow the ...

Medical research

Defense against joint degeneration

During cartilage development, chondrocytes secrete the extracellular matrix (ECM) and embed within the same environment. During progressive joint disease, such as osteoarthritis (OA), dysregulation of the process can lead ...

Arthritis & Rheumatism

Magnetic field and hydrogels could be used to grow new cartilage

Using a magnetic field and hydrogels, a team of researchers in the Perelman School of Medicine at the University of Pennsylvania have demonstrated a new possible way to rebuild complex body tissues, which could result in ...

Arthritis & Rheumatism

Is rheumatoid arthritis two different diseases?

While disease activity improves over time for most rheumatoid arthritis (RA) patients, long-term outcomes only improve in RA patients with autoantibodies, according to a new study published this week in PLOS Medicine by Xanthe ...

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