Osteoarthritis, a disease that causes severe joint pain, affects more than 20 million people in the United States. Some drug treatments can help alleviate the pain, but there are no treatments that can reverse or slow the ...
Nov 28, 2018
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During cartilage development, chondrocytes secrete the extracellular matrix (ECM) and embed within the same environment. During progressive joint disease, such as osteoarthritis (OA), dysregulation of the process can lead ...
A substance from a fungus that infects caterpillars could offer new treatment hope for sufferers of osteoarthritis according to new research.
Mar 19, 2019
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Researchers at the University of Virginia School of Medicine have identified an unexpected contributor to rheumatoid arthritis that may help explain the painful flare-ups associated with the disease. The discovery points ...
Feb 08, 2019
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In rheumatoid arthritis, immune cells called helper T cells behave differently from their counterparts in healthy cells and in other autoimmune diseases. Stanford scientists have learned why.
Feb 05, 2019
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A team of researchers from the Netherlands, the U.S. and the U.K. has found evidence that suggests tumor necrosis factor (TNF) cannot be used as a biomarker for rheumatoid arthritis (RA) treatment discontinuation. In their ...
In the largest genetic study of osteoarthritis to date, scientists have uncovered 52 new genetic changes linked to the disease, which doubles the number of genetic regions associated with the disabling condition.
Jan 21, 2019
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Spondyloarthritis is one of the most common types of chronic joint inflammation, affecting nearly 1 to 2 percent of the Western population. Cytokine blockade of tumor necrosis factor (TNF), and more recently, Interleukin-17 ...
Jan 11, 2019
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Chronic inflammatory rheumatic diseases such as rheumatoid arthritis (RA) and spondylo-arthritis (SpA) are chronic, disabling diseases with a poor outcome for loco-motoric function if left untreated. RA and SpA each affect ...
Nov 16, 2018
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A team of researchers in Belgium and the Netherlands has found that feeding a common antioxidant to test mice was effective in treating osteoarthritis. In their paper published in Science Translational Medicine, the group ...
