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Oncology & Cancer news
Oncology & Cancer
AI uncovers how DNA architecture failures trigger blood cancer
Cancer isn't just about broken genes—it's about broken architecture. Imagine a city where roads suddenly vanish, cutting off neighborhoods from essential services. That's what happens inside cells when the 3D structure ...
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Oncology & Cancer
Antibody therapy eradicates traces of multiple myeloma in preliminary trial
Treatment with an immune and cancer cell-targeting antibody therapy eradicates residual traces of the blood cell cancer multiple myeloma, according to interim results from a clinical trial conducted by researchers at Sylvester ...
12 hours ago
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Targeted alpha therapy using astatine shows promise in thyroid cancer resistant to conventional treatment
A new targeted alpha therapy is showing promise for patients whose thyroid cancer no longer responds to radioactive iodine, the standard beta-emitting treatment. In a first-in-human study, investigators found that a single ...
14 hours ago
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Gut bacteria's hidden toxin acts as DNA glue, fueling colorectal cancer risk
Colibactin is a powerful toxin produced by Escherichia coli and other bacteria living in the human gut. This highly unstable bacterial product causes mutations in DNA that have been linked to colorectal cancer. Because it ...
Structure of protein reveals how breast cancer cells survive in hostile conditions
UCLA scientists have characterized the structure and function of a key survival protein in breast cancer cells that helps explain how these tumors resist environmental stress and thrive in acidic, low-oxygen environments ...
Dec 5, 2025
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Order of cancer-driving mutations affects the chance of tumor development, study shows
The order of cancer-driving mutations—genetic changes—plays an important role in whether tumors in the intestine can develop, new research reveals.
Dec 5, 2025
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Saliva and plasma at the core of cancer detection and treatment
Saliva and plasma could be crucial in detecting recurrences or relapses of head and neck cancers, negating the need for a painful and invasive biopsy.
Dec 5, 2025
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Antibody halts triple-negative breast cancer in preclinical models
Triple-negative breast cancer (TNBC) is one of the most aggressive and treatment-resistant forms of breast cancer. It grows quickly, spreads early and lacks the hormone receptors that make other breast cancers treatable with ...
Dec 4, 2025
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New approach makes common breast cancer type responsive to immunotherapy
A study led by researchers at the Hospital del Mar Research Institute advances one of the most significant milestones in breast cancer treatment, making immunotherapy effective against the most common tumor type, estrogen ...
Dec 4, 2025
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Modified herpes virus helps destroy glioblastoma in preclinical models
Researchers at Mass General Brigham have modified a herpes simplex virus (HSV-1) that stimulates the immune system to attack glioblastoma cells. A single dose of the modified virus increased T-cell, natural killer cell, and ...
Dec 4, 2025
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A single shot of HPV vaccine may be enough to fight cervical cancer, study finds
A single HPV vaccination appears just as effective as two doses at preventing the viral infection that causes cervical cancer, researchers reported Wednesday.
Dec 4, 2025
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Machine learning reveals how disordered protein regions contribute to cancer-causing condensates
Fusion oncoproteins arise when a gene fuses with another gene and acquires new abilities. Such abilities can include the formation of biomolecular condensates, "droplets" of concentrated proteins, DNA or RNA.
Dec 4, 2025
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Protein unties tangled DNA linked to hotspots of cancer mutations
New research published in Nature Communications has linked a normal cellular process to an accumulation of DNA mutations in cancer and identified cancer-driving mutations in an underexplored part of the genome.
Dec 4, 2025
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Backup DNA repair system could be cancer's weak spot
The DNA inside our cells is constantly being damaged, and one of the worst kinds of damage is a double-strand break—when both sides of the DNA helix are cut at once. Healthy cells can normally fix these breaks using highly ...
Dec 4, 2025
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KRAS-mutant cancers: Potential target could overcome treatment resistance
Researchers at The University of Texas MD Anderson Cancer Center have identified a specific protein, RASH3D19, that is responsible for activation of RAS signaling pathways involved in aggressive tumor growth and resistance ...
Dec 4, 2025
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Exploring the link between RNA modification and prostate cancer growth
A Northwestern Medicine study published in the Journal of Clinical Investigation has uncovered a connection between a well-known cancer-related protein and a major RNA modification process, which may inform new treatment ...
Dec 4, 2025
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Simple urine test developed to screen bladder cancer
Researchers have discovered that analyzing specific patterns of cell-free DNA (cfDNA) fragmentation in a simple urine sample can effectively diagnose and stage bladder cancer, offering a much-needed alternative to invasive ...
Dec 4, 2025
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Inaugural report describes trends in pediatric cancer in U.S.
The five-year survival rate for all pediatric cancers combined reached 87% from 2015–2021, according to a first-of-its-kind report published by the American Association for Cancer Research.
Dec 4, 2025
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Update made to cervical cancer screening guideline
The American Cancer Society (ACS) released updated guidelines today for cervical cancer screening, reflecting advances in disease detection and accessibility in the United States. The updated guideline for women at average ...
Dec 4, 2025
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Biomarkers link ER+ breast cancer to neighborhood poverty
Scientists have long known that Black women with estrogen-receptor positive breast cancer and those who live in disadvantaged neighborhoods often have more aggressive forms of the disease and poorer survival rates. However, ...
Dec 4, 2025
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From lab to clinic: Phase I trial of promising combination therapy for resistant ovarian cancer
Researchers at the University of Colorado Cancer Center have discovered a novel therapy combination that could offer new hope to ovarian cancer patients who do not respond to existing treatments. Conducted entirely at the ...
Dec 4, 2025
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Rebuilding the mind after cancer: Study shows remote program could help
For many adults recovering from cancer, finishing treatment does not mean the end of challenges. Up to 80% of survivors continue to struggle with "chemobrain"—subtle but disruptive changes in memory, attention, and mental ...
Dec 4, 2025
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Expert calls for greater role of family caregivers in cancer care decisions
Health services researchers say shared decision-making (SDM)—a collaborative process where clinicians and patients make treatment choices together—should systematically include family caregivers.
Dec 4, 2025
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Women told they have dense breasts don't know what to do next, new study shows
Imagine a 57-year-old woman, let's call her Maria, who's just opened a letter about her mammography results. She's had several mammograms before, but this time reads new information: "Your breasts are dense."
Dec 4, 2025
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A common childhood virus can drive bladder cancer development
Tackling a common childhood virus could open the door to preventing bladder cancer, according to new research.
Dec 3, 2025
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