Researchers at Children's Hospital of Philadelphia (CHOP), St. Jude Children's Research Hospital (St. Jude) and the Children's Oncology Group (COG) today announced a significant paradigm shift in the understanding of T-lineage ...
Aug 14, 2024
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T-cell acute lymphoblastic leukemia (T-ALL) is an aggressive form of leukemia that arises from the malignant transformation of T-cell progenitors. This disease is most commonly diagnosed in children, where it accounts for ...
Jul 23, 2024
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While most cell types experience a functional decline after years of proliferation and replication, T cells can proliferate seemingly indefinitely and without detriment.
Jun 12, 2024
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Valrubicin, a lipophilic chemical molecule similar to daunorubicin, has primarily been used in the treatment of bladder cancer. An article recently published in Cell Death & Disease describes the repurposing of this molecule ...
Jun 6, 2024
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Leukemia is a common term used to refer to a form of blood cancer. However, there are different types of leukemia depending on the cell type involved. One unique form is myeloid/natural killer (NK) cell precursor acute leukemia ...
Jan 9, 2024
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Three young patients with relapsed T-cell leukemia have now been treated with base-edited T-cells, as part of a "bench-to-bedside" collaboration between University College London (UCL) and Great Ormond Street Hospital for ...
Jun 14, 2023
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New research led by UCL and Great Ormond Street Hospital (GOSH) to predict which childhood leukemia patients are at higher risk of not responding well to chemotherapy could allow clinicians to refine treatment strategies ...
May 5, 2023
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A team of researchers from the Cancer Science Institute of Singapore (CSI Singapore) at the National University of Singapore, led by Associate Professor Takaomi Sanda and Dr. Lim Fang Qi, has breathed new life into an existing ...
Jan 30, 2023
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Researchers of the Hospital Universitario 12 de Octubre in Madrid and the Josep Carreras Leukaemia Research Institute in Barcelona have developed a cell therapy for a type of leukemia which currently has very few treatment ...
Jan 16, 2023
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A patient with relapsed T cell leukaemia has been given base-edited T-cells in a world-first use of a base-edited cell therapy, in a 'bench-to-bedside' collaboration between UCL and Great Ormond Street Hospital for Children ...
Dec 11, 2022
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