Researchers from the Germans Trias i Pujol Research Institute (IGTP) have published a review analyzing the therapeutic potential of extracellular vesicles derived from mesenchymal stem cells to address kidney injury. The ...
Dec 2, 2025
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Serious damage to short-term kidney function—known as acute kidney injury, or AKI—can be fatal and also increase the risk of irreversible chronic kidney disease. It can be triggered by stressors ranging from sepsis to ...
Nov 12, 2025
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Montpellier University Hospital leads a 43-center French effort that reports no reduction in day 90 all-cause mortality with sodium bicarbonate infusion for critically ill adults with severe metabolic acidemia and moderate ...
Weaning patients with acute kidney injury (AKI) from dialysis while they are still hospitalized may save them from remaining on the treatment for the rest of their lives, according to a new study led by UC San Francisco.
Nov 7, 2025
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Kidney damage that seemingly heals appears to mutate the DNA in the mitochondria of kidney cells, making the organ less resilient to future stressors and reducing its function over time, a study led by UT Southwestern Medical ...
Oct 16, 2025
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A simple blood test could reveal kidney disease earlier so more can be done to halt progression, while also allowing better ongoing management of kidney health by simpler monitoring.
Oct 8, 2025
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In a new study, Yale School of Medicine (YSM) researchers unveiled a novel diagnostic method for detecting leptospiral virulence-modifying (VM) proteins in the blood and urine of hamsters, an advance that could pave the way ...
Sep 29, 2025
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When Sherry Mansour, MD, assistant professor of medicine (nephrology), first began her training at Yale, she was struck by the high rates of heart failure among her patients with kidney disease.
Sep 15, 2025
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Acute myocardial infarction and acute kidney injury are life-threatening conditions caused by ischemia, resulting from reduced or blocked blood flow to organs. Although early restoration of blood flow improves survival, many ...
Sep 2, 2025
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Acute kidney injury occurs frequently and still represents a major clinical challenge due to the lack of a targeted therapy.
Aug 13, 2025
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Acute kidney injury (AKI), previously called acute renal failure (ARF), is a rapid loss of kidney function. Its causes are numerous and include low blood volume from any cause, exposure to substances harmful to the kidney, and obstruction of the urinary tract. AKI is diagnosed on the basis of characteristic laboratory findings, such as elevated blood urea nitrogen and creatinine, or inability of the kidneys to produce sufficient amounts of urine. AKI may lead to a number of complications, including metabolic acidosis, high potassium levels, uremia, changes in body fluid balance, and effects to other organ systems. Management includes supportive care, such as renal replacement therapy, as well as treatment of the underlying disorder.
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