Medical research

Researchers find novel way to prevent drug-induced liver injury

Massachusetts General Hospital (MGH) investigators have developed a novel strategy to protect the liver from drug-induced injury and improve associated drug safety. In their report receiving advance online publication in ...

Diseases, Conditions, Syndromes

Scientists find new therapy target for drug-induced liver failure

Acetaminophen—a commonly used pain reliever and fever reducer—is the leading cause of quickly developing, or acute, liver failure in the U.S. Findings from a new mouse study suggest that treatments that increase levels ...

Health

Blue-green algae a danger for people, pets

(Medical Xpress) -- Warning signs have been showing up all summer: Several lakes and ponds in Kansas have been reporting contamination from toxic blue-green algae.

Medications

Public confused about ingredients in pain relievers

People take billions of doses of over-the-counter pain relievers like Tylenol every year, but many do not pay attention to the active ingredients they contain, such as acetaminophen, according to a new Northwestern Medicine ...

Oncology & Cancer

Study links acetaminophen to lower prostate cancer risk

A new study from American Cancer Society researchers finds use of 30 tablets a month or more of acetaminophen for five or more years was associated with an estimated 38% lower risk of prostate cancer. The study appears in ...

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Acute liver failure is the appearance of severe complications rapidly after the first signs of liver disease (such as jaundice), and indicates that the liver has sustained severe damage (loss of function of 80-90% of liver cells). The complications are hepatic encephalopathy and impaired protein synthesis (as measured by the levels of serum albumin and the prothrombin time in the blood). The 1993 classification defines hyperacute as within 1 week, acute as 8–28 days and subacute as 4–12 weeks. It reflects the fact that the pace of disease evolution strongly influences prognosis. Underlying etiology is the other significant determinant of outcome.

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