Oncology & Cancer

Chemists discover a surprising effect of a well-known leukemia drug

Researchers from RUDN University and Institute of Biomedical Chemistry of the Russian Academy of Sciences have identified an alternative mechanism for the effective antitumor drug—an enzyme called L-asparaginase. Some isoenzymes ...

Oncology & Cancer

Fat cells may inactivate chemotherapeutic drug

Adipocytes, or fat cells, can absorb and metabolize the chemotherapeutic agent daunorubicin, reducing the effectiveness of the drug and potentially contributing to poorer treatment outcomes.

Oncology & Cancer

Neurotoxicity characterized after infusion of CD19 CAR-T cells

(HealthDay)—Patients with severe neurotoxicity after infusion of CD19-targeted chimeric antigen receptor-modified T (CAR-T) cells have evidence of endothelial activation, according to a study published online Oct. 12 in ...

Oncology & Cancer

Breakthrough cancer treatment brings hope and challenges

The first gene therapy for cancer, approved by the Food Drug Administration in August, will transform the treatment of a particular kind of cancer in children and young adults. It's transformative because it uses a patient's ...

Oncology & Cancer

US clears breakthrough gene therapy for childhood leukemia

Opening a new era in cancer care, U.S. health officials have approved a breakthrough treatment that genetically engineers patients' own blood cells into an army of assassins to seek and destroy childhood leukemia.

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