Cancer

MicroRNA-TP53 circuit connected to chronic lymphocytic leukemia

The interplay between a major tumor-suppressing gene, a truncated chromosome and two sets of microRNAs provides a molecular basis for explaining the less aggressive form of chronic lymphocytic leukemia, an international team ...

Genetics

Genetics of imatinib resistance in acute lymphoblastic leukemia

In the September 15th issue of Genes & Development, Drs. Richard T. Williams, Willem den Besten, and Charles J. Sherr at Howard Hughes Medical Institute, St. Jude Children’s Research Hospital in Memphis TN, lend new insights ...

Diseases, Conditions, Syndromes

Novel M.S. Drug Shows Promise In Two Lethal Leukemias

A new study suggests that an experimental drug being tested for the treatment of multiple sclerosis and to prevent organ rejection might also help people with certain deadly forms of chronic and acute leukemia.

Cancer

Radical treatment for leukemia under way

Humanized mouse models help clarify the origins of leukemia and the cellular processes that lead to its recurrence, providing hope for a cure for this intractable blood disease.

Medical research

Major gene study uncovers secrets of leukemia

Investigators at St. Jude Children's Research Hospital have discovered previously unsuspected mutations that contribute to the formation of pediatric acute lymphoblastic leukemia (ALL), the most common cancer in children. ...

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