Medical research

How microglia contribute to Alzheimer's disease

One of the hallmarks of Alzheimer's disease is a reduction in the firing of some neurons in the brain, which contributes to the cognitive decline that patients experience. A new study from MIT shows how a type of cells called ...

Alzheimer's disease & dementia

DNA vaccine reduces both toxic proteins linked to Alzheimer's

A DNA vaccine tested in mice reduces accumulation of both types of toxic proteins associated with Alzheimer's disease, according to research that scientists say may pave the way to a clinical trial.

Alzheimer's disease & dementia

Racial differences in Alzheimer's disease unveiled

African-Americans may be twice as likely as Caucasian Americans to develop Alzheimer's disease, but nobody knows why because studies investigating the underlying causes of illness have historically drawn from a nearly all-white ...

Genetics

Newly discovered protein connected to Alzheimer's disease risk

A mutation in a newly discovered small protein is connected to a significant increase in the risk for Alzheimer's disease, expanding the known gene targets for the disease and presenting a new potential avenue for treatment, ...

Alzheimer's disease & dementia

Brain cholesterol regulates Alzheimer's plaques, study reveals

A team co-led by scientists at Scripps Research has used advanced imaging methods to reveal how the production of the Alzheimer's-associated protein amyloid beta (Aβ) in the brain is tightly regulated by cholesterol.

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