Genetics

Scientists edit gene mutations in inherited form of anemia

A Yale-led research team used a new gene editing strategy to correct mutations that cause thalassemia, a form of anemia. Their gene editing technique provided corrections to the mutations and alleviated the disease in mice, ...

Medical research

Genome engineering paves the way for sickle cell cure

A team of physicians and laboratory scientists has taken a key step toward a cure for sickle cell disease, using CRISPR-Cas9 gene editing to fix the mutated gene responsible for the disease in stem cells from the blood of ...

Cardiology

Anemic adults may have a higher risk of death after stroke

Anemia, a lack of red blood cells, may be linked to a higher risk of death in older adults who have had a stroke, according to new research in Journal of the American Heart Association, the Open Access Journal of the American ...

Diseases, Conditions, Syndromes

Variation in risk of adverse outcomes with metamizole

(HealthDay)—The magnitude of the risk of adverse outcomes associated with metamizole use varies in different studies, according to a review published online July 15 in the Journal of Clinical Pharmacy and Therapeutics.

Medical research

Male hormone reverses cell aging in clinical trial

Telomerase, an enzyme naturally found in cells, is often described as a "cellular elixir of youth." In a recent study, Brazilian and U.S. researchers show that sex hormones can stimulate production of this enzyme.

Cardiology

Anemia independently linked to high platelet reactivity in PCI

(HealthDay)—Anemia is independently associated with high platelet reactivity (HPR) and is associated with all-cause mortality and major bleeding after percutaneous coronary intervention with drug-eluting stents, according ...

Medical research

New approach could make bone marrow transplants safer

Harvard Stem Cell Institute (HSCI) scientists have taken the first steps toward developing a treatment that would make bone marrow - blood stem cell - transplantation safer and, as a result, more widely available to the millions ...

Neuroscience

Anemia negatively affects recovery from traumatic brain injuries

Approximately half of patients hospitalized with traumatic brain injuries are anemic, according to recent studies, but anemia's effects on the recovery of these patients is not clear. Now, researchers from the University ...

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