Medical research

Immunotherapy and diabetes—a game of hide and seek?

Immune checkpoint inhibitors (ICIs) are an emerging type of cancer immunotherapy that uses the immune system to attack cancer cells. However, in some patients they cause the immune system to attack healthy cells, leading ...

Arthritis & Rheumatism

Rheumatoid arthritis—can its onset be delayed or prevented?

Rheumatoid arthritis (RA) is a chronic inflammatory autoimmune disorder that leads to significant health issues as well as high treatment costs. In this themed issue of Clinical Therapeutics, experts review multiple aspects ...

Diabetes

Newly discovered immune cell linked to type 1 diabetes

In a discovery that might be likened to finding medicine's version of the Loch Ness monster, a research team from Johns Hopkins Medicine, IBM Research and four collaborating institutions is the first to document the existence ...

Immunology

New compounds could be used to treat autoimmune disorders

The immune system is programmed to rid the body of biological bad guys—like viruses and dangerous bacteria—but its precision isn't guaranteed. In the tens of millions of Americans suffering from autoimmune diseases, the ...

Diabetes

How the body protects itself from type 2 diabetes

A specific group of white blood cells, termed "regulatory T cells," keeps the immune system in balance and suppresses its activity to protect the body against autoimmune diseases. Scientists at the German Center for Neurodegenerative ...

Diabetes

Researchers identify trigger and mechanism in type 1 diabetes

Researchers at National Jewish Health have identified an elusive trigger of type 1 diabetes. A protein fragment formed in the pancreas activates the immune system's T cells, leading them to attack and destroy beta cells, ...

Immunology

How stressed-out bacteria may trigger autoimmune response

Stressful life events most likely contribute to autoimmune diseases, but scientists don't have a deep understanding of the underlying chain of events. A study on mice published this week in mSystems suggests that the gut ...

Oncology & Cancer

Major step towards individual cancer immunotherapy

Medicine has great hopes for personalised cancer immunotherapy. The idea is to have a vaccine prompt the immune system to fight a tumour. Scientists at ETH Zurich have developed a method that allows them to determine which ...

page 1 from 23