Autoimmune Diseases

Watch cancer spread in a mouse

Researchers in Japan have developed a method to image cancer at the single-cell level by using chemical techniques to make whole mouse bodies and organs highly transparent. Combining their preparation with existing imaging ...

Jul 05, 2017
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Trigger for autoimmune disease identified

Researchers at National Jewish Health have identified a trigger for autoimmune diseases such as lupus, Crohn's disease and multiple sclerosis. The findings, published in the April 2017 issue of Journal of Clinical Investigation, ...

May 11, 2017
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Antibody genes influence forgotten heart disease

New research has found that genetic differences in antibody genes alter individuals' susceptibility to rheumatic heart disease, a forgotten inflammatory heart condition – known as 'RHD' – that is rife in developing countries.

May 12, 2017
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Unmasking rogue cells in the immune system

The immune system is a formidable defense against microbial intruders, identifying and eliminating threats through an extremely intricate and adaptable network of specialized cells. However, a system of such deep complexity ...

May 30, 2017
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Antibody for fighting cancer emerges

While studying the underpinnings of multiple sclerosis, investigators at Brigham and Women's Hospital came across important clues for how to treat a very different disease: cancer. In a paper published in Science Immunology, ...

May 19, 2017
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Autoimmune diseases arise from an inappropriate immune response of the body against substances and tissues normally present in the body. In other words, the immune system mistakes some part of the body as a pathogen and attacks its own cells. This may be restricted to certain organs (e.g. in autoimmune thyroiditis) or involve a particular tissue in different places (e.g. Goodpasture's disease which may affect the basement membrane in both the lung and the kidney). The treatment of autoimmune diseases is typically with immunosuppression—medication which decreases the immune response.

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