Genetics

New genes with mutations for developmental disorders identified

The causes of intelligence impairment or epilepsy remain unexplained in more than 50% of cases. Together with international colleagues, researchers at Leipzig University Hospital have discovered two genes with mutations that ...

Medical research

Getting to the heart of heart muscle function

Every heart muscle cell, or cardiomyocyte, is studded with tiny, intricate structures called dyads. The dyads are like orchestra conductors: They coordinate incoming electrical signals with release of calcium in the muscle, ...

Diseases, Conditions, Syndromes

Monkeypox found to be evolving at a faster rate than expected

A team of researchers at the National Institute of Health Doutor Ricardo Jorge in Portugal, working with a colleague at Lusófona University, also in Portugal, has found that the monkeypox virus has been evolving at a faster ...

Diseases, Conditions, Syndromes

Pfizer says tweaked COVID-19 shots boost omicron protection

Pfizer announced Saturday that tweaking its COVID-19 vaccine to better target the omicron variant is safe and works—just days before regulators debate whether to offer Americans updated booster shots this fall.

Oncology & Cancer

Porous cells lead to poorer livers

Need another reason to think twice before ordering that extra helping of fries? It could lead to a higher risk of developing liver cancer. Cases of nonalcoholic steatohepatitis (NASH)—a type of fatty liver disease that ...

Health

Environmental factors predict risk of death: study

Along with high blood pressure, diabetes, and smoking, environmental factors such as air pollution are highly predictive of people's chances of dying, especially from heart attack and stroke, a new study shows.

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Cardiovascular disease or heart disease are a class of diseases that involve the heart or blood vessels (arteries and veins). While the term technically refers to any disease that affects the cardiovascular system (as used in MeSH C14), it is usually used to refer to those related to atherosclerosis (arterial disease). These conditions usually have similar causes, mechanisms, and treatments.

Cardiovascular diseases remain the biggest cause of deaths worldwide, though over the last two decades, cardiovascular mortality rates have declined in many high-income countries but have increased at an astonishingly fast rate in low- and middle-income countries. The percentage of premature deaths from cardiovascular disease range from 4% in high-income countries to 42% in low-income countries. More than 17 million people died from cardiovascular diseases in 2008. Each year, heart disease kills more Americans than cancer. In recent years, cardiovascular risk in women has been increasing and has killed more women than breast cancer. (PDAY) showed vascular injury accumulates from adolescence, making primary prevention efforts necessary from childhood.

By the time that heart problems are detected, the underlying cause (atherosclerosis) is usually quite advanced, having progressed for decades. There is therefore increased emphasis on preventing atherosclerosis by modifying risk factors, such as healthy eating, exercise, and avoidance of smoking.

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