Diseases, Conditions, Syndromes

Researchers identify melatonin as possible COVID-19 treatment

Results from a new Cleveland Clinic-led study suggest that melatonin, a hormone that regulates the sleep-wake cycle and is commonly used as an over-the-counter sleep aid, may be a viable treatment option for COVID-19.

Diseases, Conditions, Syndromes

Gut microbiome link to deadly chronic obstructive pulmonary disease

Research led by the Centenary Institute, the University of Technology Sydney and the University of Queensland has shown for the first time a link between chronic obstructive pulmonary disease (COPD), an often fatal lung condition, ...

Diseases, Conditions, Syndromes

What to know about pulse oximeters

(HealthDay)—If you use an oxygen concentrator and a pulse oximeter at home, proper use is crucial, the U.S. Food and Drug Administration says.

Diseases, Conditions, Syndromes

Study reveals how smoking worsens COVID-19 infection in the airways

UCLA researchers using a model of airway tissue created from human stem cells have pinpointed how smoking cigarettes causes more severe infection by SARS-CoV-2, the virus that causes COVID-19, in the airways of the lungs.

Diseases, Conditions, Syndromes

Early-life events linked to lung health in young adulthood

Early-life events, such as the exposure to air pollutants, increase the risk of chronic lung disease in young adulthood, according to new results by researchers at Karolinska Institutet, Sweden, published in the European ...

Diseases, Conditions, Syndromes

Delhi fears the worst amid smog cloud and coronavirus wave

A steady stream of patients is coming out of New Delhi's brownish atmosphere for treatment at the Breathe Better clinic, where lung specialist Davinder Kundra is confronting what he calls the "double whammy" of deadly smog ...

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Chronic obstructive pulmonary disease (COPD), also known as chronic obstructive lung disease (COLD), chronic obstructive airway disease (COAD), chronic airflow limitation (CAL) and chronic obstructive respiratory disease (CORD), is the co-occurrence of chronic bronchitis and emphysema, a pair of commonly co-existing diseases of the lungs in which the airways become narrowed. This leads to a limitation of the flow of air to and from the lungs, causing shortness of breath (dyspnea). In clinical practice, COPD is defined by its characteristically low airflow on lung function tests. In contrast to asthma, this limitation is poorly reversible and usually gets progressively worse over time. In England, an estimated 842,100 of 50 million people have a diagnosis of COPD.

COPD is caused by noxious particles or gas, most commonly from tobacco smoking, which triggers an abnormal inflammatory response in the lung.

The diagnosis of COPD requires lung function tests. Important management strategies are smoking cessation, vaccinations, rehabilitation, and drug therapy (often using inhalers). Some patients go on to require long-term oxygen therapy or lung transplantation.

Worldwide, COPD ranked as the sixth leading cause of death in 1990. It is projected to be the fourth leading cause of death worldwide by 2030 due to an increase in smoking rates and demographic changes in many countries. COPD is the third leading cause of death in the U.S. and the economic burden of COPD in the U.S. in 2007 was $42.6 billion in health care costs and lost productivity.

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