Medical research

Revealing a potential new marker for aggressive prostate cancer

Scientists are constantly looking for new ways to improve cancer treatment, particularly for aggressive tumours. But spotting which cancers are aggressive when they're first diagnosed can be tough, particularly in prostate ...

Cancer

The story of GARP: a potential target for cancer immunotherapy

Colorectal cancer is the third leading cause of cancer-related deaths in both men and women. Despite significant advances in therapies for this particular cancer, the five-year survival rate is 12 percent, according to the ...

Medications

Stress hormones promote breast cancer metastasis

It has long been thought that stress contributes to cancer progression. Scientists from the University of Basel and the University Hospital of Basel have deciphered the molecular mechanisms linking breast cancer metastasis ...

Cancer

How a common oral bacteria makes colon cancer more deadly

Researchers at the Columbia University College of Dental Medicine have determined how F. nucleatum—a common oral bacteria often implicated in tooth decay—accelerates the growth of colon cancer. The study was published ...

Cancer

Colon cancer usually diagnosed late in under-50 adults

(HealthDay)—Young adults are increasingly developing colon cancer—and it's often diagnosed at a late stage, after they've seen several doctors and been misdiagnosed, a new survey shows.

Cancer

Colon cancer growth reduced by exercise

Exercise may play a role in reducing the growth of colon cancer cells according to new research published in The Journal of Physiology. The study found that after a short session of high intensity interval training (HIIT), ...

Cancer

What you need to know about polyps in your colon

Perhaps one of the most dreaded parts of turning 50, is having to get a colonoscopy. While regular colon screening can be uncomfortable, Dr. John Kisiel, a Mayo Clinic gastroenterologist, says this screening is a crucial ...

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Colorectal cancer, commonly known as bowel cancer, is a cancer from uncontrolled cell growth in the colon, rectum, or appendix. Symptoms typically include rectal bleeding and anemia which are sometimes associated with weight loss and changes in bowel habits.

Most colorectal cancer occurs due to lifestyle and increasing age with only a minority of cases associated with underlying genetic disorders. It typically starts in the lining of the bowel and if left untreated, can grow into the muscle layers underneath, and then through the bowel wall. Screening is effective at decreasing the chance of dying from colorectal cancer and is recommended starting at the age of 50 and continuing until a person is 75 years old. Localized bowel cancer is usually diagnosed through sigmoidoscopy or colonoscopy.

Cancers that are confined within the wall of the colon are often curable with surgery while cancer that has spread widely around the body is usually not curable and management then focuses on extending the person's life via chemotherapy and improving quality of life. Colorectal cancer is the fourth most commonly diagnosed cancer in the world, but it is more common in developed countries. Around 60% of cases were diagnosed in the developed world. It is estimated that worldwide, in 2008, 1.23 million new cases of colorectal cancer were clinically diagnosed, and that it killed 608,000 people.

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