Oncology & Cancer

New drug limits cancer spreading

A research team that recently invented a drug to stop blood vessels from forming a treatment resistant barrier around some cancers has now discovered the drug can be used to prevent the cancer from spreading.

Medical research

Cell network mapping reveals rewiring in colorectal cancer

An international consortium of researchers from Australia, Ireland, the UK, Europe, and Canada, has painstakingly mapped an intracellular network that could open the door to discovering new targeted treatments for colorectal ...

Medical research

What everyone should know about cleft lip

After discussing actor Joaquin Phoenix's appearance on her talk show earlier this month, Wendy Williams received near universal condemnation for mocking those affected with cleft lip—a common birth defect in which the upper ...

Diseases, Conditions, Syndromes

China virus: What we know about the fatalities

The first fatality of China's new virus would come to represent a common set of traits for those who died to the disease: he was over the age of 60 and in poor health.

Oncology & Cancer

Can a second opinion make a difference?

Your doctor may be the smartest, most compassionate, thoughtful person in the world—a leading specialist or someone you've trusted for years. But you shouldn't let that stop you from getting a second opinion.

Oncology & Cancer

Study finds novel molecular therapeutic target for colon cancer

Researchers have found a way to help make chemotherapy more effective in treating colon cancer. They identified a new pathway (RICTOR/mTORC2) as a biological target for the disease. Targeted inhibition of RICTOR or the mTORC2 ...

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Colorectal cancer, commonly known as bowel cancer, is a cancer from uncontrolled cell growth in the colon, rectum, or appendix. Symptoms typically include rectal bleeding and anemia which are sometimes associated with weight loss and changes in bowel habits.

Most colorectal cancer occurs due to lifestyle and increasing age with only a minority of cases associated with underlying genetic disorders. It typically starts in the lining of the bowel and if left untreated, can grow into the muscle layers underneath, and then through the bowel wall. Screening is effective at decreasing the chance of dying from colorectal cancer and is recommended starting at the age of 50 and continuing until a person is 75 years old. Localized bowel cancer is usually diagnosed through sigmoidoscopy or colonoscopy.

Cancers that are confined within the wall of the colon are often curable with surgery while cancer that has spread widely around the body is usually not curable and management then focuses on extending the person's life via chemotherapy and improving quality of life. Colorectal cancer is the fourth most commonly diagnosed cancer in the world, but it is more common in developed countries. Around 60% of cases were diagnosed in the developed world. It is estimated that worldwide, in 2008, 1.23 million new cases of colorectal cancer were clinically diagnosed, and that it killed 608,000 people.

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