Psychology & Psychiatry

Looking to the cell's power generators for clues to depression

Depression is a global issue. The World Health Organization (WHO) estimates that 15 percent of people will experience a disabling bout of depression at some point in their lives. Despite an array of treatments that includes ...

Psychology & Psychiatry

Pandemic depression persists among older adults, study finds

The COVID-19 pandemic has had a significant impact on the mental health of older people living in the community, with those who are lonely faring far worse, according to new research from McMaster University.

Medications

New target identified for rapid antidepressant drugs

Vanderbilt researchers found that ketamine's rapid antidepressant action is due to specific synaptic effects. This represents a new target for drug development that could fill a major gap in care for depression.

Psychology & Psychiatry

Pandemic stress affects Black adults more than their white peers

A recent study finds that Black adults experience more pronounced mental health challenges than white adults in response to stresses associated with the COVID-19 pandemic. The study also found that younger white adults were ...

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Depression is a state of low mood and aversion to activity that can affect a person's thoughts, behaviour, feelings and physical well-being. Depressed people may feel sad, anxious, empty, hopeless, helpless, worthless, guilty, irritable, or restless. They may lose interest in activities that once were pleasurable, experience loss of appetite or overeating, or problems concentrating, remembering details or making decisions; and may contemplate or attempt suicide. Insomnia, excessive sleeping, fatigue, loss of energy, or aches, pains or digestive problems that are resistant to treatment may be present.

Depressed mood is a normal reaction to certain life events, a symptom of some medical conditions (e.g., Addison's disease, hypothyroidism), various medical treatments (e.g., hepatitis C drug therapy), and a feature of certain psychiatric syndromes.

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