Medical research

New study furthers understanding of lung regeneration

Researchers at Boston Medical Center (BMC) and Boston University (BU) have published a new study detailing the development of a method for generating human alveolar epithelial type I cells (AT1s) from pluripotent stem cells ...

Diseases, Conditions, Syndromes

New study probes macrophages' role in developing pulmonary fibrosis

Scientists have long known that white blood cells called macrophages accumulate in the lungs of people suffering from pulmonary fibrosis. What role macrophages play in developing the often fatal lung disease is less clear.

Medications

How a new drug prototype regenerates lung tissue

Pulmonary diseases are a leading cause of morbidity and mortality worldwide. For many progressive lung diseases like idiopathic pulmonary fibrosis (IPF), a key issue is a low supply of new stem cells to repair and reverse ...

Diseases, Conditions, Syndromes

Cystic fibrosis: Why infections persist despite therapy

Cystic fibrosis is a genetic disease that causes serious and sometimes fatal respiratory and digestive disorders. A new treatment, available since 2020, improves lung function and quality of life. However, it does not always ...

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Fibrosis is the formation of excess fibrous connective tissue in an organ or tissue in a reparative or reactive process. This is as opposed to formation of fibrous tissue as a normal constituent of an organ or tissue. Scarring is confluent fibrosis that obliterates the architecture of the underlying organ or tissue.

The term is also sometimes used to describe a normal healing process, but this usage is less common.

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