A team of neuroscientists have developed an intervention that normalizes multiple biological functions in mice afflicted with Fragile X Syndrome (FXS). Its breakthrough centers on protein synthesis, or the building of proteins, ...
Nov 7, 2017
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New preclinical research suggests the potential utility of BPN14770, a selective PDE4D inhibitor currently under development by Tetra Discovery Partners as a prospective treatment for memory and cognitive problems associated ...
Nov 7, 2017
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In Fragile X Syndrome—the leading genetic form of intellectual disability and autism—the effects of a single defective gene ripple through a series of chemical pathways, altering signals between brain cells. It's a complex ...
Nov 3, 2017
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The protein behind fragile X syndrome acts as a genetic conductor, orchestrating a symphony of genes that help shape DNA's 3-D structure.
Sep 28, 2017
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Fragile X syndrome—the most common heritable cause of autism spectrum disorder—is something of a phantom. It interferes with the production of a protein critical to synapse formation during a brief period in early development ...
Aug 25, 2017
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Two genes act as molecular midwives to the birth of neurons in adult mammals and when inactivated in mice cause symptoms of Fragile X Syndrome, a major cause of mental retardation, a new Yale University study has shown.
Aug 10, 2017
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Scientists have discovered how the brain can self-correct disruptions in processing, pointing the way towards possible new treatments for autism and intellectual disability.
Aug 3, 2017
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By tickling the whiskers of mice, and recording how they respond, UCLA researchers may be closer to understanding why many children with autism cover their ears when they hear loud sounds or can't tolerate scratchy wool sweaters.
Jun 12, 2017
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A widely used diabetes medication could help people with a common inherited form of autism, research shows.
May 15, 2017
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A collaboration between scientists in Belgium, the United States, Norway, France and the UK has resulted in a study that sheds light on the neural mechanisms of fragile X syndrome. This genetic disorder, which affects males ...
May 5, 2017
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