Elongated segments of DNA cause Huntington's disease and certain other disorders of the brain. Researchers funded by the SNSF have developed a method to determine the length of the mutated genes quickly and easily.
Jan 10, 2019
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Disorders of the autistic spectrum have been associated with hundreds of genetic variations, which have helped in identifying disturbed intracellular signalling pathways and molecular mechanisms typical to autism.
Dec 4, 2018
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Northwestern Medicine scientists have discovered a delay in the maturation of fast-spiking neurons in the neonatal cortex of a mouse model of Fragile X syndrome, a human neurodevelopmental disorder.
Dec 5, 2017
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New preclinical research suggests the potential utility of BPN14770, a selective PDE4D inhibitor currently under development by Tetra Discovery Partners as a prospective treatment for memory and cognitive problems associated ...
Nov 7, 2017
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The protein behind fragile X syndrome acts as a genetic conductor, orchestrating a symphony of genes that help shape DNA's 3-D structure.
Sep 28, 2017
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Two genes act as molecular midwives to the birth of neurons in adult mammals and when inactivated in mice cause symptoms of Fragile X Syndrome, a major cause of mental retardation, a new Yale University study has shown.
Aug 10, 2017
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Scientists have discovered how the brain can self-correct disruptions in processing, pointing the way towards possible new treatments for autism and intellectual disability.
Aug 3, 2017
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By tickling the whiskers of mice, and recording how they respond, UCLA researchers may be closer to understanding why many children with autism cover their ears when they hear loud sounds or can't tolerate scratchy wool sweaters.
Jun 12, 2017
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A collaboration between scientists in Belgium, the United States, Norway, France and the UK has resulted in a study that sheds light on the neural mechanisms of fragile X syndrome. This genetic disorder, which affects males ...
May 5, 2017
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Brain samples from humans show that the treatment window for Fragile X syndrome likely remains open well into maturity after childhood, when previous tests with mice indicated it might close, according to a new Drexel University-led ...
Mar 20, 2017
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