Immunology

Is there a connection between asthma and acid reflux?

Asthma and acid reflux often occur together. It isn't clear why, or whether one causes the other. But we do know that acid reflux can worsen asthma and asthma can worsen acid reflux - especially severe acid reflux, a condition ...

Diseases, Conditions, Syndromes

Risk for COVID-19 increased for adults taking PPIs

(HealthDay)—Adults taking proton pump inhibitors (PPIs) have an increased risk for having a positive COVID-19 test, with evidence of a dose-response relationship, according to a study published online July 7 in preprint ...

Diseases, Conditions, Syndromes

Could your indigestion be GERD?

(HealthDay)—Heartburn. Millions of people suffer from it. But what exactly is it and, most important, could it actually be something serious?

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Gastroesophageal reflux disease (GERD), gastro-oesophageal reflux disease (GORD), gastric reflux disease, or acid reflux disease is a chronic symptom of mucosal damage caused by stomach acid coming up from the stomach into the esophagus. A typical symptom is heartburn.

GERD is usually caused by changes in the barrier between the stomach and the esophagus, including abnormal relaxation of the lower esophageal sphincter, which normally holds the top of the stomach closed; impaired expulsion of gastric reflux from the esophagus, or a hiatal hernia. These changes may be permanent or temporary ("transient").

Another kind of acid reflux, which causes respiratory and laryngeal signs and symptoms, is called laryngopharyngeal reflux (LPR) or "extraesophageal reflux disease" (EERD). Unlike GERD, LPR is unlikely to produce heartburn, and is sometimes called silent reflux.

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