Oncology & Cancer

Innate immune landscape in glioblastoma patient tumors

Glioblastoma is an extremely aggressive brain tumor with limited treatment options. Recent progress in using immunotherapy-based treatment options in other tumor types has spurred interest in developing approaches that might ...

Oncology & Cancer

Researchers make progress in glioblastoma multiforme research

A  research team, with the participation of the University of Granada (UGR), has made some progress in determining why glioblastoma multiforme (GBM), one of the most aggressive brain tumors known, is resistant to existing ...

Oncology & Cancer

Neoadjuvant PD-1 blockade seems effective in glioblastoma

(HealthDay)—Neoadjuvant administration of programmed cell death protein 1 (PD-1) blockade seems to enhance local and systemic antitumor immune response in glioblastoma, according to a study published online Feb. 11 in Nature ...

Oncology & Cancer

Case report: Adoptive T-cell Tx shows promise in glioblastoma

(HealthDay)—Treatment with autologous chimeric antigen receptor (CAR)-engineered T cells targeting the tumor-associated antigen interleukin-13 receptor alpha 2 (IL13Rα2) is associated with tumor regression in recurrent ...

Medical research

Findings pinpoint modules that regulate glioblastoma genes

Researchers at the San Diego Supercomputer Center (SDSC), Moores Cancer Center, and Department of Neurosciences at the University of California, San Diego, have shown for the first time a pyramid hierarchical network of "coherent ...

Oncology & Cancer

Researchers find gene function 'lost' in melanoma and glioblastoma

Researchers at Georgetown University Medical Center have found a gene they say is inactivated in two aggressive cancers – malignant melanoma, a form of skin cancer, and glioblastoma multiforme, a lethal brain tumor. They ...

Oncology & Cancer

Methylation levels key to glioblastoma survival

A new study analyzing gene expression among patients with glioblastomas has found that not all of the common, deadly brain tumors appear the same upon closer examination.

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