Cardiology

What happens to young adults after a first heart attack?

Heart attacks among adults younger than 50 years of age are on the rise. In fact, the proportion of very young people has been increasing, rising by 2 percent each year for the last 10 years, according to a team of investigators ...

Cardiology

Silent heart attack may increase stroke risk

While heart attacks that cause classic symptoms such as pressure and pain in the chest are an established risk factor for stroke because they can lead to blood clot formation, new research by Weill Cornell Medicine and NewYork-Presbyterian ...

Cardiology

Blood proteins help predict risk of developing heart failure

Cardiovascular disease remains the leading cause of pain, suffering and death in the United States, and despite tremendous advances in knowledge on prevention, treatment of risk factors such as cholesterol, blood pressure ...

Health

Why lack of sleep is bad for your heart

In recent years, numerous studies have shown that people who don't get enough sleep are at greater risk of stroke and heart attack.

Cardiology

A big neck may mean you need to improve your health

Neck circumference predicts a deadly cluster of cardiovascular risk factors, according to research presented at the Asian Pacific Society of Cardiology Congress (APSC) 2019.

Cardiology

Only half of US kids and teens have ideal cholesterol levels

Cholesterol levels in U.S. youth have improved from 1999 to 2016, but only half of children and adolescents are in the ideal range and 25 percent are in the clinically high range, according to a study published in JAMA, led ...

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Myocardial infarction (MI) or acute myocardial infarction (AMI), commonly known as a heart attack, results from the interruption of blood supply to a part of the heart, causing heart cells to die. This is most commonly due to occlusion (blockage) of a coronary artery following the rupture of a vulnerable atherosclerotic plaque, which is an unstable collection of lipids (cholesterol and fatty acids) and white blood cells (especially macrophages) in the wall of an artery. The resulting ischemia (restriction in blood supply) and ensuing oxygen shortage, if left untreated for a sufficient period of time, can cause damage or death (infarction) of heart muscle tissue (myocardium).

Classical symptoms of acute myocardial infarction include sudden chest pain (typically radiating to the left arm or left side of the neck), shortness of breath, nausea, vomiting, palpitations, sweating, and anxiety (often described as a sense of impending doom). Women may experience fewer typical symptoms than men, most commonly shortness of breath, weakness, a feeling of indigestion, and fatigue. Approximately one-quarter of all myocardial infarctions are "silent", that is without chest pain or other symptoms.

Among the diagnostic tests available to detect heart muscle damage are an electrocardiogram (ECG), echocardiography, cardiac MRI and various blood tests. The most often used blood markers are the creatine kinase-MB (CK-MB) fraction and the troponin levels. Immediate treatment for suspected acute myocardial infarction includes oxygen, aspirin, and sublingual nitroglycerin.

Most cases of STEMI (ST elevation MI) are treated with thrombolysis or percutaneous coronary intervention (PCI). NSTEMI (non-ST elevation MI) should be managed with medication, although PCI is often performed during hospital admission. In people who have multiple blockages and who are relatively stable, or in a few emergency cases, bypass surgery may be an option, especially in diabetics.

Heart attacks are the leading cause of death for both men and women worldwide. Important risk factors are previous cardiovascular disease, older age, tobacco smoking, high blood levels of certain lipids (triglycerides, low-density lipoprotein) and low levels of high density lipoprotein (HDL), diabetes, high blood pressure, obesity, chronic kidney disease, heart failure, excessive alcohol consumption, the abuse of certain drugs (such as cocaine and methamphetamine), and chronic high stress levels.

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