Medications

Obesity and medication: When does bodyweight matter?

How can we best treat infectious diseases in people with obesity? Hospital pharmacist and Ph.D. researcher Koen van Rhee studied how obesity affects blood levels of two commonly used medicines. He also developed a method ...

Pediatrics

Teen sleep troubles explained

Many teens have a hard time winding down at bedtime. This can prevent them from getting the recommended amount of sleep they need every night. Many teens report difficulty concentrating at school, daytime sleepiness and fatigue.

Health

Q&A: Staying heart healthy during American Heart Month

February is American Heart Month—a perfect opportunity for members of the George Washington University community to take a closer look at our own cardiovascular care. GW Today spoke to Andrew Choi, co-director of multimodality ...

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Hypertension (HTN) or high blood pressure, sometimes arterial hypertension, is a chronic medical condition in which the blood pressure in the arteries is elevated. This requires the heart to work harder than normal to circulate blood through the blood vessels. Blood pressure involves two measurements, systolic and diastolic, which depend on whether the heart muscle is contracting (systole) or relaxed (diastole) between beats. Normal blood pressure is at or below 120/80 mmHg. High blood pressure is said to be present if it is persistently at or above 140/90 mmHg.

Hypertension is classified as either primary (essential) hypertension or secondary hypertension; about 90–95% of cases are categorized as "primary hypertension" which means high blood pressure with no obvious underlying medical cause. The remaining 5–10% of cases (secondary hypertension) are caused by other conditions that affect the kidneys, arteries, heart or endocrine system.

Hypertension is a major risk factor for stroke, myocardial infarction (heart attacks), heart failure, aneurysms of the arteries (e.g. aortic aneurysm), peripheral arterial disease and is a cause of chronic kidney disease. Even moderate elevation of arterial blood pressure is associated with a shortened life expectancy. Dietary and lifestyle changes can improve blood pressure control and decrease the risk of associated health complications, although drug treatment is often necessary in patients for whom lifestyle changes prove ineffective or insufficient.

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