A common human gene mutation combination—found in about 5% of the U.K.'s Black population as well as millions of people worldwide with recent African ancestry—has been linked to a number of health conditions and poor ...
Feb 15, 2024
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A new, single-dose, oral treatment for sleeping sickness is as effective as current treatments and could be a key factor in eliminating disease transmission by 2030, suggests a new study published in The Lancet Infectious ...
Nov 29, 2022
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Scientists say they are a step closer to developing a drug to kill the trypanosome parasite that causes human African trypanosomiasis, otherwise known as sleeping sickness, paving the way for a potential cure.
Jul 13, 2020
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Researchers have turned a fungus into a disease-curing factory through modern genetic engineering and patience. The natural antibiotic is a promising cure for a neglected tropical disease called human African trypanosomiasis, ...
Apr 4, 2019
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(Medical Xpress)—A new study led by University of Pennsylvania researchers involves a classic case of evolution's fickle nature: a genetic mutation that protects against a potentially fatal infectious disease also appears ...
Jul 31, 2013
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Sleeping sickness kills tens of thousands of people in Africa each year. Current chemotherapies are subject to various limitations, including resistance. Rhodesain, an enzyme of the parasites that cause this illness (human ...
May 17, 2013
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Research led by scientists at the London School of Hygiene & Tropical Medicine has exploited a revolutionary genetic technique to discover how human African Trypanosomiasis (HAT) drugs target the parasite which causes the ...
Jan 25, 2012
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Several diseases have been earmarked for elimination or eradication based on factors such as feasibility, lives saved and the possibility of long-run cost-savings. The cost of elimination strategies, however, can become very ...
Dec 13, 2021
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A newly published extensive body of research into Human African trypanosomiasis (HAT), also known as sleeping sickness, has revealed new insights into the deadly parasitic disease that threatens the lives of millions of people ...
Nov 8, 2021
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Over the past twenty years, huge efforts by a broad coalition of stakeholders, coordinated by the World Health Organization have curbed the latest epidemic of human African trypanosomiasis, a lethal disease transmitted by ...
May 21, 2020
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Human African trypanosomiasis, sleeping sickness, African lethargy, or Congo trypanosomiasis is a parasitic disease of people and animals, caused by protozoa of the species Trypanosoma brucei and transmitted by the tsetse fly. The disease is endemic in some regions of sub-Saharan Africa, covering about 37 countries and 60 million people. It is estimated that 50,000 to 70,000 people are currently infected, the number having declined somewhat in recent years. The number of reported cases was below 10,000 in 2009, the first time in 50 years. It is believed that many cases go unreported. About 48,000 people died of it in 2008. Four major epidemics have occurred in recent history: one from 1896–1906 primarily in Uganda and the Congo Basin, two epidemics in 1920 and 1970 in several African countries, and a recent 2008 epidemic in Uganda.
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