Obstetrics & gynaecology
Important cause of preeclampsia discovered
Despite being the subject of increasing interest for a whole century, how preeclampsia develops has been unclear—until now.
Jan 21, 2021
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8
Inflammation
Medical research
Inflamed environment is Clostridioides difficile paradise
A new study from North Carolina State University shows that the inflammation caused by Clostridioides difficile (C. diff) infection gives the pathogen a two-fold advantage: by both creating an inhospitable environment for ...
Jan 19, 2021
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43
Medical research
Blood may hold clues to some of COVID-19's most mysterious symptoms
The most severe cases of COVID-19 begin with leaky blood vessels. Breaches in the vascular system cause inflammation and coagulation, as fluid floods the lungs. Meanwhile, a host of seemingly unrelated symptoms set in. Blood ...
Jan 18, 2021
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71
Immunology
New insights into the control of inflammation
Scientists at The Wistar Institute discovered that Early Growth Response 1 (EGR1), a protein that turns on and off specific genes during blood cell development, inhibits expression of pro-inflammatory genes in macrophages. ...
Jan 13, 2021
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48
Diabetes
Early research shows promise for therapeutics that delay type 2 diabetes
Vanderbilt researchers have discovered a unique pathway that initiates islet β cell inflammation—a hallmark of type 2 diabetes—putting them a step closer to developing targeted therapeutics for the disease that affects ...
Jan 13, 2021
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25
Gastroenterology
Study reveals new details about how bacterial toxins cause life-threatening colitis
Research led by scientists from UCLA and Harvard University has uncovered details about how the bacterium Clostridioides difficile causes excessive inflammation in the gut that can lead to potentially deadly colitis. Studying ...
Jan 8, 2021
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3
Diseases, Conditions, Syndromes
Dental experts discover biological imbalance is the link between gum and kidney disease
An imbalance of the body's oxygen producing free radicals and its antioxidant cells could be the reason why gum disease and chronic kidney disease affect each other, a new study led by the University of Birmingham has found.
Jan 5, 2021
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6
Medications
Inflammation from ADT may cause fatigue in prostate cancer patients
Prostate cancer is one of the most common cancers among men in the U.S. For many patients, hormone therapy is a treatment option. This type of therapy, also called androgen deprivation therapy (ADT), reduces the level of ...
Jan 4, 2021
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20
Overweight & Obesity
Blood vessel cells implicated in chronic inflammation of obesity
Dec. 30, 2020—When fat cells in the body are stuffed with excess fat, the surrounding tissue becomes inflamed. That chronic, low-level inflammation is one of the driving factors behind many of the diseases associated with ...
Dec 31, 2020
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143
Inflammatory disorders
The two sides of inflammation—the cure and the curse
One of the many wonders—and mysteries—of human biology is the complex response of the innate immune system, which is known for its swiftness in annihilating invading pathogens and capacity to mount an explosive inflammatory ...
