Scientists who analyzed the genes involved in 10 autoimmune diseases that begin in childhood have discovered 22 genome-wide signals shared by two or more diseases. These shared gene sites may reveal potential new targets ...
Aug 24, 2015
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Scientists have been finding that genetic risk for many diseases lies primarily in noncoding parts of the genome, which used to be called "junk DNA," and not in the genes themselves. But that finding naturally begs more questions ...
Jul 31, 2015
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(HealthDay)—For children with polyarticular juvenile idiopathic arthritis (JIA), discontinuing medications is challenging, with high relapse rates, especially after discontinuation of tumor necrosis factor inhibitor (TNFi) ...
Jun 19, 2015
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The results of a study presented today at the European League Against Rheumatism Annual Congress (EULAR 2015) demonstrated the value of a new interactive iPad app that helps young people with Juvenile Idiopathic Arthritis ...
Jun 11, 2015
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Hip replacement is often performed in patients with juvenile arthritis when their joints have been severely damaged by the disease. A study at Hospital for Special Surgery (HSS) finds that the procedure is an excellent option ...
Mar 24, 2015
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When you think of hip replacement surgery, you generally envision an older adult with painful osteoarthritis. But the procedure is also used for younger patients with juvenile idiopathic arthritis (JIA) whose joints have ...
Nov 17, 2014
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Data presented today at the European League Against Rheumatism Annual Congress (EULAR 2014) demonstrate the possibility of using biomarkers (developed from whole blood gene expression profiles) in children with juvenile idiopathic ...
Jun 13, 2014
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A new study published in the current issue of the Journal of the American Association for Pediatric Ophthalmology and Strabismus (AAPOS) suggests that the biologic agent adalimumab may be a viable treatment option for patients ...
Oct 22, 2013
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In the U.S., there are nearly 300,000 children with juvenile arthritis and other rheumatic illnesses according to estimates from the American College of Rheumatology (ACR). For pediatric patients with systemic juvenile idiopathic ...
Sep 24, 2013
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The joints of children with the most common form of chronic inflammatory arthritis contain immune cells that resemble those of 90-year-olds, according to a new study led by researchers at Children's Hospital of Pittsburgh ...
Jul 29, 2013
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