Scientists at St. Jude Children's Research Hospital have comprehensively identified genes directly regulated by a protein associated with high-risk pediatric leukemias. High-risk leukemias, particularly MLL-rearranged (MLL-r) ...
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Each year, about 13,000 people in Germany are diagnosed with leukemia, an umbrella term that encompasses various forms of blood cancer. Among those affected are also many children and adolescents under 15 years of age. A ...
Nov 27, 2023
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Patients with indolent non-Hodgkin lymphomas (iNHL) report considerable psychological distress, according to a study published online Nov. 3 in The Oncologist.
Nov 21, 2023
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Leukemia is the most common type of cancer in children. Treatment involves intensive chemotherapy, which has severe side effects due to its non-specific mode of action.
Nov 20, 2023
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Some patients with myelodysplastic syndromes, like acute myeloid leukemia, benefit from a chemotherapy drug called decitabine that stunts cancer growth. But many others are resistant to decatibine's effects or become resistant ...
Nov 16, 2023
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When Mauricio Ferrato completed his doctorate in computer and information sciences at the University of Delaware a few months ago, he made his mark in more ways than one.
Nov 15, 2023
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A team at Weill Cornell Medicine has mapped the location and spatial features of blood-forming cells within human bone marrow. Their findings confirm hypotheses about the anatomy of this tissue and provide a powerful new ...
Nov 14, 2023
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A novel assay that detects a unique molecular marker in patients with acute myeloid leukemia (AML) may revolutionize the way this disease is detected and treated according to a new report in The Journal of Molecular Diagnostics. ...
Nov 13, 2023
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A new editorial perspective titled "C/EBPβ cooperates with MYB to maintain the oncogenic program of AML cells" has been published in Oncotarget.
Nov 13, 2023
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A new editorial paper was published in Oncotarget, titled "Impact of SHP2 tyrosine phosphorylation on the development of acquired resistance to allosteric SHP2 inhibitors."
Nov 8, 2023
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Leukemia (American English) or leukaemia (British English) (from the Greek leukos λεύκος - white, and haima αίμα - blood) is a type of cancer of the blood or bone marrow characterized by an abnormal increase of immature white blood cells called "blasts". Leukemia is a broad term covering a spectrum of diseases. In turn, it is part of the even broader group of diseases affecting the blood, bone marrow, heart, and lymphoid system, which are all known as hematological neoplasms. Leukemia can also cause multiple organ failure.
In 2000, approximately 256,000 children and adults around the world developed some form of leukemia, and 209,000 died from it.[citation needed]
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