Medical research

Could leukemia be stopped before it starts?

Acute myeloid leukemia (AML), a blood cancer affecting both adults and children, requires more than one genetic "hit" to develop. As we age, many of us acquire a mutation that enables certain of our blood cells to multiply ...

Oncology & Cancer

Mutation's role in blood cancers revealed by ideal team-up

A genetic mutation that disrupts how DNA sends messages to the rest of a cell has been linked to a large number of blood cancers. Thanks to a collaboration between biologists at Cold Spring Harbor Laboratory (CSHL) and an ...

Oncology & Cancer

Vitamin B6, leukemia's deadly addiction

Scientists have discovered that Acute Myeloid Leukemia (AML) grows by taking advantage of the B6 vitamin to accelerate cell division. The research team from Cold Spring Harbor Laboratory (CSHL) and Memorial Sloan Kettering ...

Oncology & Cancer

When cells cycle fast, cancer gets a jumpstart

The progression of cancer has been studied extensively, and the key steps in this journey have been well mapped, at least in some solid tumors: Lesions to genes that confer risk of cancer accumulate and alter normal cell ...

Medications

Cocktail proves toxic to leukemia cells

A combination of drugs that affect mitochondria—the power plants inside cells—may become the best weapons yet to fight acute myeloid leukemia, according to Rice University researchers.

Oncology & Cancer

Leukemia drug shows promise for treating a childhood brain cancer

A drug used to treat chronic myeloid leukemia appears to be more effective at stopping a type of medulloblastoma in mouse models than existing treatments for the deadly pediatric brain tumor, reports a multi-institutional ...

Oncology & Cancer

Making cancer stem cells visible to the immune system

Leukemia stem cells protect themselves against the immune defense by suppressing a target molecule for killer cells. This protective mechanism can be tricked with drugs. In the journal Nature, scientists from Basel, Tübingen ...

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