The sex hormone estrogen has a negative impact on heartbeat regulation, according to an experimental study from Linköping University, Sweden, published in Science Advances. Estrogen impact seems to interact with hereditary ...
Mar 15, 2023
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An over-the-counter cough suppressant can knock some heart cells back into rhythm, a finding that may lead to a new way to treat a rare heart condition called long QT syndrome.
Feb 18, 2022
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Dozens of commonly used drugs, including antibiotics, antinausea and anticancer medications, have a potential side effect of lengthening the electrical event that triggers contraction, creating an irregular heartbeat, or ...
May 14, 2021
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Geneticists and heart specialists around the world had previously reported 17 genes to cause long QT syndrome, a little-known inherited heart condition. However, the Clinical Genome Resource's (ClinGen) expert panel has critically ...
Jan 27, 2020
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Although DNA testing is becoming increasingly quick, cheap and easy to perform, the results are sometimes ambiguous: Gene mutations called "variants of uncertain significance" can create uncertainty about a patient's risk ...
Jun 26, 2018
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Researchers at Columbia University Medical Center and the Data Science Institute at Columbia University have uncovered a potentially dangerous drug interaction using data science. Their findings were published in the latest ...
Oct 10, 2016
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Researchers have solved the mystery of an infant with severe long QT syndrome, found to be caused by a lethal genetic defect in only 8 percent of her cells.
Sep 27, 2016
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A genetic variant linked to sudden cardiac death leads to protein overproduction in heart cells, Johns Hopkins scientists report. Unlike many known disease-linked variants, this one lies not in a gene but in so-called noncoding ...
May 27, 2014
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(Medical Xpress) -- Johns Hopkins researchers have discovered a new drug that may be useful in treating a heart rhythm condition called long QT syndrome. The study was published online on June 28 in the Early Edition of the ...
Aug 1, 2012
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Sudden cardiac death is always a shocking, tragic event, especially when it occurs at a young age. But, for the first time, scientists are unraveling how genetic defects can help predict the risk of dying suddenly in individuals ...
May 10, 2011
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The long QT syndrome (LQTS) is a rare inborn heart condition in which delayed repolarization of the heart following a heartbeat increases the risk of episodes of torsade de pointes (TDP, a form of irregular heartbeat that originates from the ventricles). These episodes may lead to palpitations, fainting and sudden death due to ventricular fibrillation. Episodes may be provoked by various stimuli, depending on the subtype of the condition.
The condition is so named because of the appearances of the electrocardiogram (ECG/EKG), on which there is prolongation of the QT interval. In some individuals the QT prolongation occurs only after the administration of certain medications.
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