Sophie Walton Bernstedt from the Gastroenterology and Rheumatology Unit at the Department of Medicine, Huddinge (MedH), is defending her thesis "Risk factors for colorectal cancer and the impact on life in Lynch syndrome," ...
May 21, 2024
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Researchers from Mayo Clinic Comprehensive Cancer Center and Mayo Clinic Center for Individualized Medicine have discovered new genetic markers to identify Lynch syndrome-associated colorectal cancer with high accuracy. Studies ...
Sep 20, 2023
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Among individuals who consented to whole-exome sequencing and were identified as carriers of predisposition genes for hereditary breast and ovarian cancer (HBOC) or Lynch syndrome, 39.2% would not have qualified for genetic ...
Apr 18, 2023
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People with Lynch syndrome have a higher hereditary risk of colon cancer. Despite regular endoscopic surveillance, it remains elevated in those affected. Researchers at the National Center for Hereditary Tumor Diseases (NZET) ...
Dec 28, 2022
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One in five GPs could be unwilling to prescribe aspirin to patients with a cancer-causing syndrome, despite national guidelines advising it, new research has found. The findings are published in the British Journal of General ...
Dec 15, 2022
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Scientists from the Heidelberg Institute for Theoretical Studies (HITS), the German Cancer Research Center (DKFZ), the Heidelberg University Hospital and Heidelberg University have established INDICATE, an international collaborative ...
Oct 21, 2022
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For patients with Lynch syndrome (LS), daily resistant starch (RS) seems to have a lasting protective effect against noncolorectal cancers, according to a study published online July 25 in Cancer Prevention Research.
Aug 18, 2022
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Researchers have developed a new fluorescent label that gives a clearer picture of how DNA architecture is disrupted in cancer cells. The findings could improve cancer diagnoses for patients and classification of future cancer ...
Mar 4, 2022
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Up to 38.6% of people with colon cancer who have a hereditary cancer syndrome—including 6.3% of those with Lynch syndrome—could have their conditions remain undetected with current universal tumor-screening methods, and ...
May 17, 2021
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The first UK study to estimate the proportion of womb cancers caused by an inherited cancer predisposition called Lynch syndrome has been carried out by The University of Manchester.
Sep 18, 2020
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Lynch syndrome (HNPCC or Hereditary nonpolyposis colorectal cancer ) is an autosomal dominant genetic condition which has a high risk of colon cancer as well as other cancers including endometrium, ovary, stomach, small intestine, hepatobiliary tract, upper urinary tract, brain, and skin. The increased risk for these cancers is due to inherited mutations that impair DNA mismatch repair.
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