Researchers have developed a new therapy that can be injected intravenously right after a heart attack to promote healing and prevent heart failure.
Apr 25, 2025
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Vision changes are an inevitable part of aging, but why are some more susceptible to age-related eye diseases and why do some individuals experience more severe decline than others? New research from The Jackson Laboratory ...
Feb 18, 2025
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Our brain and eyes can play tricks on us—not least when it comes to the expanding hole illusion. A new computational model developed by Flinders University experts helps to explain how cells in the human retina make us ...
Feb 14, 2025
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Nearly every disease has an inflammatory component, but blood tests can't pinpoint inflammation in specific organs or tissues in the human body.
Feb 6, 2025
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A multidisciplinary team of researchers from the Istituto Italiano di Tecnologia (IIT-Italian Institute of Technology) and IRCCS Ospedale Policlinico San Martino has demonstrated the effectiveness of the Ziapin2 molecule ...
Jan 21, 2025
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University of California San Diego researchers have identified a U-shaped association between high-density lipoprotein (HDL) levels and age-related macular degeneration (AMD) risk, with lower incidence of AMD in the middle ...
Researchers have developed a therapy to treat Stargardt disease, the most common form of inherited macular degeneration, which often leads to vision loss. Their study shows promising results using a precise technique for ...
Jan 10, 2025
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A research team co-led by the University of California, Irvine has discovered that accumulated DNA damage in the retina is a key contributor to age-related macular degeneration and that targeting specific retinal cell types ...
Dec 3, 2024
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Light therapy could be a useful treatment for the most common form of age-related macular degeneration, a new study says.
Oct 22, 2024
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A novel free eye disease screening program is engaging adults at high risk for eye disease who are underusing eye care services, according to a study published online Aug. 22 in JAMA Ophthalmology.
Aug 27, 2024
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Age-related macular degeneration (AMD) is a medical condition which usually affects older adults and results in a loss of vision in the center of the visual field (the macula) because of damage to the retina. It occurs in “dry” and “wet” forms. It is a major cause of blindness and visual impairment in older adults (>50 years). Macular degeneration can make it difficult or impossible to read or recognize faces, although enough peripheral vision remains to allow other activities of daily life.
Starting from the inside of the eye and going towards the back, the three main layers at the back of the eye are the retina, which contains the nerves; the choroid, which contains the blood supply; and the sclera, which is the white of the eye.
The macula is the central area of the retina, which provides the most detailed central vision.
In the dry (nonexudative) form, cellular debris called drusen accumulate between the retina and the choroid, and the retina can become detached. In the wet (exudative) form, which is more severe, blood vessels grow up from the choroid behind the retina, and the retina can also become detached. It can be treated with laser coagulation, and with medication that stops and sometimes reverses the growth of blood vessels.
Although some macular dystrophies affecting younger individuals are sometimes referred to as macular degeneration, the term generally refers to age-related macular degeneration (AMD or ARMD).
Age-related macular degeneration begins with characteristic yellow deposits (drusen) in the macula, between the retinal pigment epithelium and the underlying choroid. Most people with these early changes (referred to as age-related maculopathy) have good vision. People with drusen can go on to develop advanced AMD. The risk is considerably higher when the drusen are large and numerous and associated with disturbance in the pigmented cell layer under the macula. Recent research suggests that large and soft drusen are related to elevated cholesterol deposits and may respond to cholesterol-lowering agents.
This text uses material from Wikipedia licensed under CC BY-SA
