Medical research

Active substance from plant slows down aggressive eye cancer

An active substance that has been known for 30 years could unexpectedly turn into a ray of hope against eye tumors. This is shown by a study conducted by researchers from the Universities of Bonn and Magdeburg together with ...

Cancer

Reprograming T cells to attack solid tumors

An attractive approach to liver cancer treatment is to bolster the body's own immune defenses. Now an international team involving A*STAR researchers has genetically engineered human T cells to endow them with both specificity ...

Cancer

The story of GARP: a potential target for cancer immunotherapy

Colorectal cancer is the third leading cause of cancer-related deaths in both men and women. Despite significant advances in therapies for this particular cancer, the five-year survival rate is 12 percent, according to the ...

Cancer

New studies aim to improve melanoma diagnosis

A pair of studies led by University of North Carolina Lineberger Comprehensive Cancer Center researchers could aid in improved diagnosis for melanoma, the deadliest form of skin cancer.

Cancer

Physical combination multiplies melanoma risk

The risk of developing melanoma is significantly multiplied for people who have red hair and more than 20 large moles, University of Queensland researchers have found.

Cancer

Artificial intelligence could predict spread of melanoma

An interdisciplinary team of researchers at Ben-Gurion University of the Negev (BGU) in Israel and the University of Texas Southwestern Medical Center (UTSW) in Dallas have developed groundbreaking technology to identify ...

Cancer

Low-cost 'cancer probe' could spot deadly melanoma early

Melanoma, the deadliest form of skin cancer, is diagnosed in more than 130,000 people globally every year. Now, work is being done on a tool to help in its early detection: a simple, compact laser probe that can distinguish ...

Diseases, Conditions, Syndromes

Poor kidney function linked to higher cancer risk

A new study has uncovered a modestly higher cancer risk in individuals with mild to severe chronic kidney disease, driven primarily by skin (non-melanoma) and urogenital cancers. The findings, which appear in an upcoming ...

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Melanoma i/ˌmɛləˈnoʊmə/ (from Greek μέλας - melas, "dark") is a malignant tumor of melanocytes. Melanocytes are cells that produce the dark pigment, melanin, which is responsible for the color of skin. They predominantly occur in skin, but are also found in other parts of the body, including the bowel and the eye (see uveal melanoma). Melanoma can occur in any part of the body that contains melanocytes.

Melanoma is less common than other skin cancers. However, it is much more dangerous and causes the majority (75%) of deaths related to skin cancer. Worldwide, doctors diagnose about 160,000 new cases of melanoma yearly. The diagnosis is more frequent in women than in men and is particularly common among Caucasians living in sunny climates, with high rates of incidence in Australia, New Zealand, North America, Latin America, and northern Europe. According to a WHO report, about 48,000 melanoma related deaths occur worldwide per year.

The treatment includes surgical removal of the tumor, adjuvant treatment, chemo- and immunotherapy, or radiation therapy. The chance of a cure is greatest when the tumor is discovered while it is still small and thin, and can be entirely removed surgically.

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